Interstitial lung disease and obstructive sleep apnea

Yet H. Khor; Christopher J. Ryerson; Shane A. Landry; Mark E. Howard; Thomas J. Churchward; Bradley A. Edwards; Garun S. Hamilton; Simon A. Joosten

doi:10.1016/j.smrv.2021.101442

Interstitial lung disease and obstructive sleep apnea

Yet H. Khor, Christopher J. Ryerson, Shane A. Landry, Mark E. Howard, Thomas J. Churchward, Bradley A. Edwards, Garun S. Hamilton, Simon A. Joosten

Research output: Contribution to journal › Review Article › Research › peer-review

32 Citations (Scopus)

Abstract

Obstructive sleep apnea (OSA) is one of the most common comorbidities in patients with interstitial lung disease (ILD). Growing evidence highlights the significance of sleep disturbance on health outcomes in this population. The relationships between ILD and OSA are complex and possibly bidirectional, with multiple mechanisms postulated for the pathogenic and physiologic links. This review synthesizes current evidence and hypotheses regarding different aspects of the relationships between ILD and OSA, emphasizing the interactions between epidemiology, pathogenesis, and pathophysiology.

Original language	English
Article number	101442
Number of pages	9
Journal	Sleep Medicine Reviews
Volume	58
DOIs	https://doi.org/10.1016/j.smrv.2021.101442
Publication status	Published - 2021

Keywords

Interstitial lung disease
Obstructive sleep apnea
Pulmonary fibrosis
Sleep

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10.1016/j.smrv.2021.101442

Cite this

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title = "Interstitial lung disease and obstructive sleep apnea",

abstract = "Obstructive sleep apnea (OSA) is one of the most common comorbidities in patients with interstitial lung disease (ILD). Growing evidence highlights the significance of sleep disturbance on health outcomes in this population. The relationships between ILD and OSA are complex and possibly bidirectional, with multiple mechanisms postulated for the pathogenic and physiologic links. This review synthesizes current evidence and hypotheses regarding different aspects of the relationships between ILD and OSA, emphasizing the interactions between epidemiology, pathogenesis, and pathophysiology.",

keywords = "Interstitial lung disease, Obstructive sleep apnea, Pulmonary fibrosis, Sleep",

author = "Khor, \{Yet H.\} and Ryerson, \{Christopher J.\} and Landry, \{Shane A.\} and Howard, \{Mark E.\} and Churchward, \{Thomas J.\} and Edwards, \{Bradley A.\} and Hamilton, \{Garun S.\} and Joosten, \{Simon A.\}",

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doi = "10.1016/j.smrv.2021.101442",

language = "English",

volume = "58",

journal = "Sleep Medicine Reviews",

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T1 - Interstitial lung disease and obstructive sleep apnea

AU - Khor, Yet H.

AU - Ryerson, Christopher J.

AU - Landry, Shane A.

AU - Howard, Mark E.

AU - Churchward, Thomas J.

AU - Edwards, Bradley A.

AU - Hamilton, Garun S.

AU - Joosten, Simon A.

PY - 2021

Y1 - 2021

N2 - Obstructive sleep apnea (OSA) is one of the most common comorbidities in patients with interstitial lung disease (ILD). Growing evidence highlights the significance of sleep disturbance on health outcomes in this population. The relationships between ILD and OSA are complex and possibly bidirectional, with multiple mechanisms postulated for the pathogenic and physiologic links. This review synthesizes current evidence and hypotheses regarding different aspects of the relationships between ILD and OSA, emphasizing the interactions between epidemiology, pathogenesis, and pathophysiology.

AB - Obstructive sleep apnea (OSA) is one of the most common comorbidities in patients with interstitial lung disease (ILD). Growing evidence highlights the significance of sleep disturbance on health outcomes in this population. The relationships between ILD and OSA are complex and possibly bidirectional, with multiple mechanisms postulated for the pathogenic and physiologic links. This review synthesizes current evidence and hypotheses regarding different aspects of the relationships between ILD and OSA, emphasizing the interactions between epidemiology, pathogenesis, and pathophysiology.

KW - Interstitial lung disease

KW - Obstructive sleep apnea

KW - Pulmonary fibrosis

KW - Sleep

UR - http://www.scopus.com/inward/record.url?scp=85100410225&partnerID=8YFLogxK

U2 - 10.1016/j.smrv.2021.101442

DO - 10.1016/j.smrv.2021.101442

M3 - Review Article

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AN - SCOPUS:85100410225

SN - 1087-0792

VL - 58

JO - Sleep Medicine Reviews

JF - Sleep Medicine Reviews

M1 - 101442

ER -

Interstitial lung disease and obstructive sleep apnea

Abstract

Keywords

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Other files and links

Improving treatment efficacy and outcomes in obstructive sleep apnoea by targeting treatment to the underlying physiological abnormality

Improving the treatment efficacy and cardiovascular burden of obstructive sleep apnoea through the development of clinically predictive tools based on the underlying physiology

Cite this

Interstitial lung disease and obstructive sleep apnea

Abstract

Keywords

Access to Document

Other files and links

Projects

Improving treatment efficacy and outcomes in obstructive sleep apnoea by targeting treatment to the underlying physiological abnormality

Improving the treatment efficacy and cardiovascular burden of obstructive sleep apnoea through the development of clinically predictive tools based on the underlying physiology

Cite this