TY - JOUR
T1 - International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015
T2 - Device-associated module
AU - Rosenthal, Víctor Daniel
AU - Al-Abdely, Hail M.
AU - El-Kholy, Amani Ali
AU - AlKhawaja, Safa A.Aziz
AU - Leblebicioglu, Hakan
AU - Mehta, Yatin
AU - Rai, Vineya
AU - Hung, Nguyen Viet
AU - Kanj, Souha Sami
AU - Salama, Mona Foda
AU - Salgado-Yepez, Estuardo
AU - Elahi, Naheed
AU - Morfin Otero, Rayo
AU - Apisarnthanarak, Anucha
AU - De Carvalho, Braulio Matias
AU - Ider, Bat Erdene
AU - Fisher, Dale
AU - Buenaflor, Maria Carmen S.G.
AU - Petrov, Michael M.
AU - Quesada-Mora, Ana Marcela
AU - Zand, Farid
AU - Gurskis , Vaidotas
AU - Anguseva, Tanja
AU - Ikram, Aamer
AU - Aguilar de Moros, Daisy
AU - Duszynska, Wieslawa
AU - Mejia, Nepomuceno
AU - Horhat, Florin George
AU - Belskiy, Vladislav
AU - Mioljevic, Vesna
AU - Di Silvestre, Gabriela
AU - Furova, Katarina
AU - Ramos-Ortiz, Gloria Y.
AU - Gamar Elanbya, May Osman
AU - Satari, Hindra Irawan
AU - Gupta, Umesh
AU - Dendane, Tarek
AU - Raka, Lul
AU - Guanche-Garcell, Humberto
AU - Hu, Bijie
AU - Padgett, Denis
AU - Jayatilleke, Kushlani
AU - Ben Jaballah, Najla
AU - Apostolopoulou, Eleni
AU - Prudencio Leon, Walter Enrique
AU - Sepulveda-Chavez, Alejandra
AU - Telechea, Hector Miguel
AU - Trotter, Andrew
AU - Alvarez-Moreno, Carlos
AU - Kushner-Davalos, Luis
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically.
AB - Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically.
KW - Antibiotic resistance
KW - Bloodstream infection
KW - Catheter-associated urinary tract infection
KW - Central line-associated bloodstream infections
KW - Developing countries
KW - Health care-associated infection
KW - Hospital infection
KW - Limited resources countries
KW - Urinary tract infection
KW - Ventilator-associated pneumonia
UR - http://www.scopus.com/inward/record.url?scp=84998546960&partnerID=8YFLogxK
U2 - 10.1016/j.ajic.2016.08.007
DO - 10.1016/j.ajic.2016.08.007
M3 - Article
AN - SCOPUS:84998546960
VL - 44
SP - 1495
EP - 1504
JO - American Journal of Infection Control
JF - American Journal of Infection Control
SN - 0196-6553
IS - 12
ER -
