TY - JOUR
T1 - Intercycle variability of the ovarian response in patients undergoing repeated stimulation with corifollitropin alfa in a gonadotropin-releasing hormone antagonist protocol
AU - Rombauts, Luk
AU - Lambalk, Cornelius B
AU - Schultze-Mosgau, Askan
AU - van Kuijk, Jacqueline
AU - Verweij, Pierre
AU - Gates, Davis
AU - Gordon, Keith
AU - Griesinger, Georg
PY - 2015
Y1 - 2015
N2 - To determine whether individual subject variation in ovarian response between repeated cycles with the same ovarian stimulation protocol can be predicted.
DESIGN:
Retrospective data analysis.
SETTING:
Multicenter, open-label, uncontrolled clinical trial.
PATIENT(S):
Women aged 18-39 from a phase 3, open-label, uncontrolled trial with complete data across all cycles (n = 176).
INTERVENTION(S):
Up to three cycles of a single injection of 150 ?g corifollitropin alfa for 7 days, then daily recombinant FSH/hMG until three follicles reached =17 mm. Gonadotropin-releasing hormone antagonist from stimulation day 5 until day of hCG administration.
MAIN OUTCOME MEASURE(S):
Numbers of follicles =11 mm on day of hCG in cycles 1-3, transition in ovarian response type between cycles from low (0-
AB - To determine whether individual subject variation in ovarian response between repeated cycles with the same ovarian stimulation protocol can be predicted.
DESIGN:
Retrospective data analysis.
SETTING:
Multicenter, open-label, uncontrolled clinical trial.
PATIENT(S):
Women aged 18-39 from a phase 3, open-label, uncontrolled trial with complete data across all cycles (n = 176).
INTERVENTION(S):
Up to three cycles of a single injection of 150 ?g corifollitropin alfa for 7 days, then daily recombinant FSH/hMG until three follicles reached =17 mm. Gonadotropin-releasing hormone antagonist from stimulation day 5 until day of hCG administration.
MAIN OUTCOME MEASURE(S):
Numbers of follicles =11 mm on day of hCG in cycles 1-3, transition in ovarian response type between cycles from low (0-
UR - http://www.sciencedirect.com/science/article/pii/S0015028215004549
UR - https://www.scopus.com/pages/publications/84942837036
U2 - 10.1016/j.fertnstert.2015.06.027
DO - 10.1016/j.fertnstert.2015.06.027
M3 - Article
SN - 0015-0282
VL - 104
SP - 884
EP - 890
JO - Fertility and Sterility
JF - Fertility and Sterility
IS - 4 (Art. ID: e2)
ER -