Insulin action in the brain: Roles in energy and glucose homeostasis

G. T. Dodd; T. Tiganis

doi:10.1111/jne.12513

Insulin action in the brain: Roles in energy and glucose homeostasis

G. T. Dodd, T. Tiganis

Research output: Contribution to journal › Review Article › Other › peer-review

68 Citations (Scopus)

Abstract

A growing body of evidence from research in rodents and humans has identified insulin as an important neuoregulatory peptide in the brain, where it coordinates diverse aspects of energy balance and peripheral glucose homeostasis. This review discusses where and how insulin interacts within the brain and evaluates the physiological and pathophysiological consequences of central insulin signalling in metabolism, obesity and type 2 diabetes.

Original language	English
Article number	e12513
Number of pages	13
Journal	Journal of Neuroendocrinology
Volume	29
Issue number	10
DOIs	https://doi.org/10.1111/jne.12513
Publication status	Published - 1 Oct 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

AgRP
energy homeostasis
glucose homeostasis
hypothalamus
insulin
POMC

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10.1111/jne.12513

240547317-oaFinal published version, 479 KB

Cite this

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KW - glucose homeostasis

KW - hypothalamus

KW - insulin

KW - POMC

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M3 - Review Article

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Insulin action in the brain: Roles in energy and glucose homeostasis

Abstract

UN SDGs

Keywords

Access to Document

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