Initiation of breathing at birth

Arjan B. te Pas; Stuart Hooper

doi:10.1017/9781139680349.010

Initiation of breathing at birth

Arjan B. te Pas, Stuart Hooper

Obstetrics & Gynaecology Monash Health

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Research › peer-review

1 Citation (Scopus)

Abstract

Recent animal and human studies have challenged some of the prevailing concepts regarding the major physiological changes that characterize the transition to life after birth. In this chapter we will explain in detail how the breathing effort initiates a pulmonary and hemodynamic cascade of events that is of vital importance for survival after birth. The role of cord clamping and its effects on the hemodynamic transition will be discussed. This chapter also covers the pathophysiology of preterm infants failing transition and the current strategies caregivers can use to support them. Finally, we describe how positive pressure ventilation (PPV) can cause not only lung injury, but can also adversely affect cardiovascular function and initiate a systemic inflammatory cascade that can injure the immature brain.

Original language	English
Title of host publication	Fetal and Neonatal Lung Development
Subtitle of host publication	Clinical Correlates and Technologies for the Future
Editors	Alan H. Jobe, Jeffrey A. Whitsett, Steven H. Abman
Place of Publication	New York, NY
Publisher	Cambridge University Press
Pages	164-186
Number of pages	23
ISBN (Electronic)	9781139680349
ISBN (Print)	9781107072091
DOIs	https://doi.org/10.1017/9781139680349.010
Publication status	Published - 18 Apr 2016

Keywords

Birth
Brain injury
Breathing
Cord clamping
Lung aeration
Lung injury
Lung liquid
Newborn
Pulmonary vascular resistance
Respiratory distress syndrome

Access to Document

10.1017/9781139680349.010

Link to publication in Scopus

Cite this

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Initiation of breathing at birth. / te Pas, Arjan B.; Hooper, Stuart.

Fetal and Neonatal Lung Development: Clinical Correlates and Technologies for the Future. ed. / Alan H. Jobe; Jeffrey A. Whitsett; Steven H. Abman. New York, NY : Cambridge University Press, 2016. p. 164-186.

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Research › peer-review

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