Inhibitory Activity of Antibacterial Mouthwashes and Antiseptic Substances against Neisseria gonorrhoeae

Eloise Williams; Bowen Zhang; Eric P.F. Chow; Socheata Chea; Tiffany R. Phillips; Kate Maddaford; Marcelina Krysiak; Yi Nong; Helen Stefanatos; Shivani Pasricha; Christopher K. Fairley; Deborah A. Wiliamson

doi:10.1128/aac.00042-22

Inhibitory Activity of Antibacterial Mouthwashes and Antiseptic Substances against Neisseria gonorrhoeae

Eloise Williams
, Bowen Zhang
, Eric P.F. Chow
, Socheata Chea
, Tiffany R. Phillips
, Kate Maddaford
, Marcelina Krysiak
, Yi Nong
, Helen Stefanatos
, Shivani Pasricha
, Christopher K. Fairley
, Deborah A. Wiliamson

Melbourne Sexual Health Centre

Research output: Contribution to journal › Article › Research › peer-review

4 Citations (Scopus)

Abstract

Improved treatment and prevention strategies, such as antimicrobial mouthwashes, may be important for addressing the public health threat of antimicrobial-resistant Neisseria gonorrhoeae. Here, we describe the activity of seven common antibacterial mouthwashes and antiseptics against N. gonorrhoeae isolates, incorporating the use of a human saliva test matrix. Our data demonstrate that antibacterial mouthwashes and antiseptics vary in their ability to inhibit the in vitro growth of N. gonorrhoeae and saliva may impact this inhibitory activity.

Original language	English
Article number	e0004222
Number of pages	6
Journal	Antimicrobial Agents and Chemotherapy
Volume	66
Issue number	6
DOIs	https://doi.org/10.1128/aac.00042-22
Publication status	Published - 21 Jun 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Neisseria gonorrhoeae
prevention
public health
sexually transmitted diseases

Access to Document

10.1128/aac.00042-22Licence: CC BY

Cite this

Williams, E., Zhang, B., Chow, E. P. F., Chea, S., Phillips, T. R., Maddaford, K., Krysiak, M., Nong, Y., Stefanatos, H., Pasricha, S., Fairley, C. K., & Wiliamson, D. A. (2022). Inhibitory Activity of Antibacterial Mouthwashes and Antiseptic Substances against Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy, 66(6), Article e0004222. https://doi.org/10.1128/aac.00042-22

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title = "Inhibitory Activity of Antibacterial Mouthwashes and Antiseptic Substances against Neisseria gonorrhoeae",

abstract = "Improved treatment and prevention strategies, such as antimicrobial mouthwashes, may be important for addressing the public health threat of antimicrobial-resistant Neisseria gonorrhoeae. Here, we describe the activity of seven common antibacterial mouthwashes and antiseptics against N. gonorrhoeae isolates, incorporating the use of a human saliva test matrix. Our data demonstrate that antibacterial mouthwashes and antiseptics vary in their ability to inhibit the in vitro growth of N. gonorrhoeae and saliva may impact this inhibitory activity.",

keywords = "Neisseria gonorrhoeae, prevention, public health, sexually transmitted diseases",

author = "Eloise Williams and Bowen Zhang and Chow, \{Eric P.F.\} and Socheata Chea and Phillips, \{Tiffany R.\} and Kate Maddaford and Marcelina Krysiak and Yi Nong and Helen Stefanatos and Shivani Pasricha and Fairley, \{Christopher K.\} and Wiliamson, \{Deborah A.\}",

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month = jun,

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doi = "10.1128/aac.00042-22",

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AU - Williams, Eloise

AU - Zhang, Bowen

AU - Chow, Eric P.F.

AU - Chea, Socheata

AU - Phillips, Tiffany R.

AU - Maddaford, Kate

AU - Krysiak, Marcelina

AU - Nong, Yi

AU - Stefanatos, Helen

AU - Pasricha, Shivani

AU - Fairley, Christopher K.

AU - Wiliamson, Deborah A.

PY - 2022/6/21

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AB - Improved treatment and prevention strategies, such as antimicrobial mouthwashes, may be important for addressing the public health threat of antimicrobial-resistant Neisseria gonorrhoeae. Here, we describe the activity of seven common antibacterial mouthwashes and antiseptics against N. gonorrhoeae isolates, incorporating the use of a human saliva test matrix. Our data demonstrate that antibacterial mouthwashes and antiseptics vary in their ability to inhibit the in vitro growth of N. gonorrhoeae and saliva may impact this inhibitory activity.

KW - Neisseria gonorrhoeae

KW - prevention

KW - public health

KW - sexually transmitted diseases

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M3 - Article

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AN - SCOPUS:85132455141

SN - 0066-4804

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M1 - e0004222

ER -

Inhibitory Activity of Antibacterial Mouthwashes and Antiseptic Substances against Neisseria gonorrhoeae

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

A multidisciplinary approach to understanding the transmission dynamics and the control of sexually transmitted infections

Optimising the control and management of sexually transmitted infections through research and innovation

Cite this

Inhibitory Activity of Antibacterial Mouthwashes and Antiseptic Substances against Neisseria gonorrhoeae

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Projects

A multidisciplinary approach to understanding the transmission dynamics and the control of sexually transmitted infections

Optimising the control and management of sexually transmitted infections through research and innovation

Cite this