Inhibition by serum of autoimmune aspermatogenic orchitis

C. C. Bernard, F. Toullet, G. Lamoureux

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Inhibition by serum of experimental autoimmune orchitis (EAO) was studied in guinea pigs. It was found that the capacity of an autoantigen, antigen P, purified from guinea pigs spermatozoa, to produce lesions of EAO could be inhibited by mixing antigen P with a small amount of normal human serum before injection into guinea pigs. In protected animals, cell mediated immunity and humoral antibodies to antigen P were also significantly suppressed.

Original languageEnglish
Pages (from-to)245-250
Number of pages6
JournalAustralian Journal of Experimental Biology and Medical Science
Volume53
Issue number3
Publication statusPublished - 1975
Externally publishedYes

Cite this

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abstract = "Inhibition by serum of experimental autoimmune orchitis (EAO) was studied in guinea pigs. It was found that the capacity of an autoantigen, antigen P, purified from guinea pigs spermatozoa, to produce lesions of EAO could be inhibited by mixing antigen P with a small amount of normal human serum before injection into guinea pigs. In protected animals, cell mediated immunity and humoral antibodies to antigen P were also significantly suppressed.",
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Inhibition by serum of autoimmune aspermatogenic orchitis. / Bernard, C. C.; Toullet, F.; Lamoureux, G.

In: Australian Journal of Experimental Biology and Medical Science, Vol. 53, No. 3, 1975, p. 245-250.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Inhibition by serum of autoimmune aspermatogenic orchitis

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AU - Toullet, F.

AU - Lamoureux, G.

PY - 1975

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N2 - Inhibition by serum of experimental autoimmune orchitis (EAO) was studied in guinea pigs. It was found that the capacity of an autoantigen, antigen P, purified from guinea pigs spermatozoa, to produce lesions of EAO could be inhibited by mixing antigen P with a small amount of normal human serum before injection into guinea pigs. In protected animals, cell mediated immunity and humoral antibodies to antigen P were also significantly suppressed.

AB - Inhibition by serum of experimental autoimmune orchitis (EAO) was studied in guinea pigs. It was found that the capacity of an autoantigen, antigen P, purified from guinea pigs spermatozoa, to produce lesions of EAO could be inhibited by mixing antigen P with a small amount of normal human serum before injection into guinea pigs. In protected animals, cell mediated immunity and humoral antibodies to antigen P were also significantly suppressed.

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