Inhibition by serum of autoimmune aspermatogenic orchitis

C. C. Bernard, F. Toullet, G. Lamoureux

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Abstract

Inhibition by serum of experimental autoimmune orchitis (EAO) was studied in guinea pigs. It was found that the capacity of an autoantigen, antigen P, purified from guinea pigs spermatozoa, to produce lesions of EAO could be inhibited by mixing antigen P with a small amount of normal human serum before injection into guinea pigs. In protected animals, cell mediated immunity and humoral antibodies to antigen P were also significantly suppressed.

Original languageEnglish
Pages (from-to)245-250
Number of pages6
JournalAustralian Journal of Experimental Biology and Medical Science
Volume53
Issue number3
Publication statusPublished - 1975
Externally publishedYes

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