Influenza epidemiology, vaccine coverage and vaccine effectiveness in sentinel Australian hospitals in 2013: the Influenza Complications Alert Network

Allen Cheuk-Seng Cheng, Dominic E Dwyer, Mark Holmes, Louis B Irving, Simon G A Brown, Grant W Waterer, Tony Korman, Cameron Hunter, Saliya Hewagama, Nadia Deborah Sarah Friedman, Peter Wark, Graham Simpson, John Upham, Simon Bowler, Sanjaya N Senenayake, Anastase Thomas Christos Kotsimbos, Paul M Kelly

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Abstract

The National Influenza Program aims to reduce serious morbidity and mortality from influenza by providing public funding for vaccination to at-risk groups. The Influenza Complications Alert Network (FluCAN) is a sentinel hospital-based surveillance program that operates at 14 sites in all states and territories in Australia. This report summarises the epidemiology of hospitalisations with confirmed influenza, estimates vaccine coverage and influenza vaccine protection against hospitalisation with influenza during the 2013 influenza season. In this observational study, cases were defined as patients admitted to one of the sentinel hospitals, with influenza confirmed by nucleic acid testing. Controls were patients who had acute respiratory illnesses who were testnegative for influenza. Vaccine effectiveness was estimated as 1 minus the odds ratio of vaccination in case patients compared with control patients, after adjusting for known confounders. During the period 5 April to 31 October 2013, 631 patients were admitted with confirmed influenza at the 14 FluCAN sentinel hospitals. Of these, 31 were more than 65 years of age, 9.5 were Indigenous Australians, 4.3 were pregnant and 77 had chronic co-morbidities. Influenza B was detected in 30 of patients. Vaccination coverage was estimated at 81 in patients more than 65 years of age but only 49 in patients aged less than 65 years with chronic comorbidities. Vaccination effectiveness against hospitalisation with influenza was estimated at 50 (95 confidence interval: 33 , 63 , P
Original languageEnglish
Pages (from-to)E143 - E149
Number of pages7
JournalCommunicable Diseases Intelligence Quarterly Report
Volume38
Issue number2
Publication statusPublished - 2014

Cite this