Influence of systolic blood pressure on clinical outcomes in elderly heart failure patients treated with nebivolol: data from the SENIORS trial

Manuel Montero-Perez-Barquero, Marcus Flather, Michael Roughton, Andrew Justin Stewart Coats, Michael Bohm, Dirk Jan van Veldhuisen, Daphne Babalis, Alain Cohen-Solal, Luis Manzano

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    Aims There is limited information about the effects of beta-blockers in heart failure (HF) stratified by blood pressure, especially in the elderly and those with preserved EF. We evaluate the effects of nebivolol on outcomes in elderly patients with HF stratified by baseline systolic blood pressure (SBP) and EF. Methods and results The SENIORS trial evaluated the effects of nebivolol and enrolled 2128 patients =70 years of age with HF. Patients were divided into three baseline pre-treatment SBP categories (130 mmHg). In addition, we evaluated the influence of SBP (=130 and >130 mmHg) on patients with LVEF
    Original languageEnglish
    Pages (from-to)1009 - 1015
    Number of pages7
    JournalEuropean Journal of Heart Failure
    Issue number9
    Publication statusPublished - 2014

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