Infection in ventricular assist devices: Prevention and treatment

William L. Holman, Barry K. Rayburn, David C. McGiffin, Brian A. Foley, Raymond L. Benza, Robert C. Bourge, Laura J. Pinderski, James K. Kirklin

Research output: Contribution to journalArticleResearchpeer-review

89 Citations (Scopus)


Infection is one of the most important challenges to the use of implanted mechanical circulatory support systems (MCSS), particularly as we enter the era of permanent device use in patients who are not candidates for cardiac transplantation. This paper describes the pathogenesis of MCSS infection, with particular attention to the role of biofilm-forming bacteria. Suggestions are presented for the prevention and treatment of infections in implanted MCSS.

Original languageEnglish
Pages (from-to)S48-S57
Number of pages10
JournalThe Annals of Thoracic Surgery
Issue number6 SUPPL.
Publication statusPublished - 1 Jun 2003
Externally publishedYes

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