Indomethacin vs ibuprofen: comparison of efficacy in the setting of conservative therapeutic approach

Andra Malikiwi, Charlene Roufaeil, Kenneth Hark Hong Tan, Arvind Sehgal

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)


Indomethacin has been the mainstay for medical closure of patent ductus arteriosus. With its discontinuation, many units shifted to the use ibuprofen. We compared the therapeutic efficacy (successful closure, a priori defined as complete closure or >50 reduction in size) and the impact of the two drugs on neonatal morbidities.
Original languageEnglish
Pages (from-to)615 - 620
Number of pages6
JournalEuropean Journal of Pediatrics
Issue number5
Publication statusPublished - 2015

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