To investigate the impact of a change in the proportions of lipid, surfactant and co-solvent on the solubilisation capacity of self-emulsifying formulations of danazol during in vitro dispersion and digestion studies and correlation with in vivo bioavailability in beagle dogs
|Pages (from-to)||748 - 757|
|Number of pages||10|
|Publication status||Published - 2007|
Cuine, J., Charman, W. N., Pouton, C. W., Edwards, G. A., & Porter, C. J. (2007). Increasing the proportional content of surfactant (Cremophor EL) relative to lipid in self-emulsifying lipid-based formulations of danazol reduces oral bioavailability in beagle dogs. Pharmaceutical Research, 24(4), 748 - 757.