Increased vascular access complications in patients with renal dysfunction (full title below)

Emad F. Aziz, Sandeep Pulimi, Clinton Coleman, Calatin Florita, Dan Musat, Deborah Tormey, Ashraf Fawzy, Steve Lee, Eyal Herzog, David L. Coven, Jacqueline E. Tamis-Holland, Mun K. Hong

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17 Citations (Scopus)


Background: Arteriotomy closure device (ACD) use has increased following percutaneous transfemoral coronary procedures (PTCP). However, their safety in patients with chronic kidney disease (CKD) is not known. Therefore, we evaluated the complication rates of ACD among patients with CKD. Methods: Six-hundred ten consecutive patients who underwent PTCP and ACD were retrospectively studied. Patients were grouped according to their creatinine clearance (CrCl in ml/min/1.73 m2) calculated by the Cockcroft-Gault formula using the National Kidney Foundation classification system; Stage I (CrCl ≥ 90); Stage II (60-89); Stage III (30-59); Stage IV (15-29); and Stage V (≤ 15). The primary endpoint was the combined incidence of pseudo-aneurysm, retroperitoneal hematoma, femoral artery thrombosis, surgical vascular repair, and groin infection. Results: Among 610 patients 283 (46%) underwent PCI. The primary endpoint was seen in 66 (10.8%) patients. Univariate predictors of primary outcome were lower.

Original languageEnglish
Pages (from-to)8-13
Number of pages6
JournalJournal of Invasive Cardiology
Issue number1
Publication statusPublished - Jan 2010
Externally publishedYes


  • Cardiac catheterization
  • Closure devices
  • Kidney disease
  • Vascular complications

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