Increase in visceral and subcutaneous abdominal fat in men with prostate cancer treated with androgen deprivation therapy

Emma Hamilton, Emily Gianatti, Boyd Strauss, John Wentworth, Daryl Lim Joon, Damien Bolton, Jeffrey Zajac, Mathis Grossmann

Research output: Contribution to journalArticleResearchpeer-review

128 Citations (Scopus)

Abstract

Androgen deprivation therapy (ADT) for prostate cancer is associated with increases in fat mass and risk of type 2 diabetes; however, the relationship between sex steroid deficiency and abdominal fat distribution remains controversial. DESIGN: We conducted a 12-month prospective observational study at a tertiary referral centre. PATIENTS AND MEASUREMENTS: We investigated changes in abdominal fat distribution and insulin resistance in 26 men (70.6A?6.8 years) with nonmetastatic prostate cancer during the first year of ADT.
Original languageEnglish
Pages (from-to)377 - 383
Number of pages7
JournalClinical Endocrinology
Volume74
Issue number3
DOIs
Publication statusPublished - 2011

Cite this