Incorporation of [U-13C]glycerol defines plausible early steps for the biosynthesis of methylenomycin A in Streptomyces coelicolor A3(2)

G. L. Challis, K. F. Chater

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6 Citations (Scopus)

Abstract

Incorporation of [U-13C]glycerol into the linear plasmid-encoded secondary metabolite methylenomycin A, both intact and indirectly via metabolism to acetyl CoA, was observed in Streptomyces coelicolor suggesting plausible early biosynthetic steps for this unusual antibiotic.

Original languageEnglish
Pages (from-to)935-936
Number of pages2
JournalChemical Communications
Issue number10
DOIs
Publication statusPublished - 21 May 2001
Externally publishedYes

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