Incidence of chronic kidney disease among people with diabetes

a systematic review of observational studies

Research output: Contribution to journalReview ArticleResearchpeer-review

19 Citations (Scopus)

Abstract

Aims: The aim was to systematically review published articles that reported the incidence of chronic kidney disease among people with diabetes. Methods: A systematic literature search was performed using MEDLINE, Embase and CINAHL databases. The titles and abstracts of all publications identified by the search were reviewed and 10 047 studies were retrieved. Results: A total of 71 studies from 30 different countries with sample sizes ranging from 505 to 211 132 met the inclusion criteria. The annual incidence of microalbuminuria and albuminuria ranged from 1.3% to 3.8% for Type 1 diabetes. For Type 2 diabetes and studies combining both diabetes types, the range was from 3.8% to 12.7%, with four of six studies reporting annual rates between 7.4% and 8.6%. In studies reporting the incidence of eGFR < 60 ml/min/1.73 m2 using the Modification of Diet on Renal Disease (MDRD) equation, apart from one study which reported an annual incidence of 8.9%, the annual incidence ranged from 1.9% to 4.3%. The annual incidence of end-stage renal disease ranged from 0.04% to 1.8%. Conclusions: The annual incidence of microalbuminuria and albuminuria is ~ 2–3% in Type 1 diabetes, and ~ 8% in Type 2 diabetes or mixed diabetes type. The incidence of developing eGFR < 60 ml/min/1.73 m2 is ~ 2–4% per year. Despite the wide variation in methods and study design, within a particular category of kidney disease, there was only modest variation in incidence rates. These findings may be useful in clinical settings to help understand the risk of developing kidney disease among those with diabetes.

Original languageEnglish
Pages (from-to)887-901
Number of pages15
JournalDiabetic Medicine
Volume34
Issue number7
DOIs
Publication statusPublished - 1 Jul 2017

Cite this

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title = "Incidence of chronic kidney disease among people with diabetes: a systematic review of observational studies",
abstract = "Aims: The aim was to systematically review published articles that reported the incidence of chronic kidney disease among people with diabetes. Methods: A systematic literature search was performed using MEDLINE, Embase and CINAHL databases. The titles and abstracts of all publications identified by the search were reviewed and 10 047 studies were retrieved. Results: A total of 71 studies from 30 different countries with sample sizes ranging from 505 to 211 132 met the inclusion criteria. The annual incidence of microalbuminuria and albuminuria ranged from 1.3{\%} to 3.8{\%} for Type 1 diabetes. For Type 2 diabetes and studies combining both diabetes types, the range was from 3.8{\%} to 12.7{\%}, with four of six studies reporting annual rates between 7.4{\%} and 8.6{\%}. In studies reporting the incidence of eGFR < 60 ml/min/1.73 m2 using the Modification of Diet on Renal Disease (MDRD) equation, apart from one study which reported an annual incidence of 8.9{\%}, the annual incidence ranged from 1.9{\%} to 4.3{\%}. The annual incidence of end-stage renal disease ranged from 0.04{\%} to 1.8{\%}. Conclusions: The annual incidence of microalbuminuria and albuminuria is ~ 2–3{\%} in Type 1 diabetes, and ~ 8{\%} in Type 2 diabetes or mixed diabetes type. The incidence of developing eGFR < 60 ml/min/1.73 m2 is ~ 2–4{\%} per year. Despite the wide variation in methods and study design, within a particular category of kidney disease, there was only modest variation in incidence rates. These findings may be useful in clinical settings to help understand the risk of developing kidney disease among those with diabetes.",
author = "Koye, {D. N.} and Shaw, {J. E.} and Reid, {C. M.} and Atkins, {R. C.} and Reutens, {A. T.} and Magliano, {D. J.}",
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Incidence of chronic kidney disease among people with diabetes : a systematic review of observational studies. / Koye, D. N.; Shaw, J. E.; Reid, C. M.; Atkins, R. C.; Reutens, A. T.; Magliano, D. J.

In: Diabetic Medicine, Vol. 34, No. 7, 01.07.2017, p. 887-901.

Research output: Contribution to journalReview ArticleResearchpeer-review

TY - JOUR

T1 - Incidence of chronic kidney disease among people with diabetes

T2 - a systematic review of observational studies

AU - Koye, D. N.

AU - Shaw, J. E.

AU - Reid, C. M.

AU - Atkins, R. C.

AU - Reutens, A. T.

AU - Magliano, D. J.

PY - 2017/7/1

Y1 - 2017/7/1

N2 - Aims: The aim was to systematically review published articles that reported the incidence of chronic kidney disease among people with diabetes. Methods: A systematic literature search was performed using MEDLINE, Embase and CINAHL databases. The titles and abstracts of all publications identified by the search were reviewed and 10 047 studies were retrieved. Results: A total of 71 studies from 30 different countries with sample sizes ranging from 505 to 211 132 met the inclusion criteria. The annual incidence of microalbuminuria and albuminuria ranged from 1.3% to 3.8% for Type 1 diabetes. For Type 2 diabetes and studies combining both diabetes types, the range was from 3.8% to 12.7%, with four of six studies reporting annual rates between 7.4% and 8.6%. In studies reporting the incidence of eGFR < 60 ml/min/1.73 m2 using the Modification of Diet on Renal Disease (MDRD) equation, apart from one study which reported an annual incidence of 8.9%, the annual incidence ranged from 1.9% to 4.3%. The annual incidence of end-stage renal disease ranged from 0.04% to 1.8%. Conclusions: The annual incidence of microalbuminuria and albuminuria is ~ 2–3% in Type 1 diabetes, and ~ 8% in Type 2 diabetes or mixed diabetes type. The incidence of developing eGFR < 60 ml/min/1.73 m2 is ~ 2–4% per year. Despite the wide variation in methods and study design, within a particular category of kidney disease, there was only modest variation in incidence rates. These findings may be useful in clinical settings to help understand the risk of developing kidney disease among those with diabetes.

AB - Aims: The aim was to systematically review published articles that reported the incidence of chronic kidney disease among people with diabetes. Methods: A systematic literature search was performed using MEDLINE, Embase and CINAHL databases. The titles and abstracts of all publications identified by the search were reviewed and 10 047 studies were retrieved. Results: A total of 71 studies from 30 different countries with sample sizes ranging from 505 to 211 132 met the inclusion criteria. The annual incidence of microalbuminuria and albuminuria ranged from 1.3% to 3.8% for Type 1 diabetes. For Type 2 diabetes and studies combining both diabetes types, the range was from 3.8% to 12.7%, with four of six studies reporting annual rates between 7.4% and 8.6%. In studies reporting the incidence of eGFR < 60 ml/min/1.73 m2 using the Modification of Diet on Renal Disease (MDRD) equation, apart from one study which reported an annual incidence of 8.9%, the annual incidence ranged from 1.9% to 4.3%. The annual incidence of end-stage renal disease ranged from 0.04% to 1.8%. Conclusions: The annual incidence of microalbuminuria and albuminuria is ~ 2–3% in Type 1 diabetes, and ~ 8% in Type 2 diabetes or mixed diabetes type. The incidence of developing eGFR < 60 ml/min/1.73 m2 is ~ 2–4% per year. Despite the wide variation in methods and study design, within a particular category of kidney disease, there was only modest variation in incidence rates. These findings may be useful in clinical settings to help understand the risk of developing kidney disease among those with diabetes.

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U2 - 10.1111/dme.13324

DO - 10.1111/dme.13324

M3 - Review Article

VL - 34

SP - 887

EP - 901

JO - Diabetic Medicine

JF - Diabetic Medicine

SN - 0742-3071

IS - 7

ER -