Incidence and seroprevalence of dengue virus infections in Australian travellers to Asia

I Ratnam; J Black; Karin Leder; Beverley-Ann Biggs; Elizabeth Matchett; Alexander A Padiglione; Ian John Woolley; T Panagiotidis; T Gheradin; L Pollissard; C Demont; C Luxemburger; Joseph Torresi

doi:10.1007/s10096-011-1429-1

Incidence and seroprevalence of dengue virus infections in Australian travellers to Asia

I Ratnam, J Black, Karin Leder, Beverley-Ann Biggs, Elizabeth Matchett, Alexander A Padiglione, Ian John Woolley, T Panagiotidis, T Gheradin, L Pollissard, C Demont, C Luxemburger, Joseph Torresi

Epidemiology and Preventive Medicine Alfred Hospital

Research output: Contribution to journal › Article › Research › peer-review

33 Citations (Scopus)

Abstract

The purpose of this study was to estimate the incidence density and prevalence of dengue virus infection in Australian travellers to Asia. We conducted a multi-centre prospective cohort study of Australian travellers over a 32-month period. We recruited 467 travellers (=16 years of age) from three travel clinics who intended to travel Asia, and 387 (82.9 ) of those travellers completed questionnaires and provide samples pre- and post-travel for serological testing for dengue virus infection. Demographic data, destination countries and history of vaccinations and flavivirus infections were obtained. Serological testing for dengue IgG and IgM by enzyme-linked immunosorbent assay (ELISA) (PanBio assay) was performed. Acute seroconversion for dengue infection was demonstrated in 1.0 of travellers, representing an incidence of 3.4 infections per 10,000 days of travel (95 confidence interval [CI]: 0.9?8.7). The seroprevalence of dengue infection was 4.4 and a greater number of prior trips to Asia was a predictor for dengue seroprevalence (p=0.019). All travellers experienced subclinical dengue infections and had travelled to India (n=3) and China (n=1). This significant attack rate of dengue infection can be used to advise prospective travellers to dengue-endemic countries.

Original language	English
Pages (from-to)	1203 - 1210
Number of pages	8
Journal	European Journal of Clinical Microbiology and Infectious Diseases
Volume	31
Issue number	6
DOIs	https://doi.org/10.1007/s10096-011-1429-1
Publication status	Published - 2012

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10.1007/s10096-011-1429-1

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Ratnam, I., Black, J., Leder, K., Biggs, B.-A., Matchett, E., Padiglione, A. A., Woolley, I. J., Panagiotidis, T., Gheradin, T., Pollissard, L., Demont, C., Luxemburger, C., & Torresi, J. (2012). Incidence and seroprevalence of dengue virus infections in Australian travellers to Asia. European Journal of Clinical Microbiology and Infectious Diseases, 31(6), 1203 - 1210. https://doi.org/10.1007/s10096-011-1429-1

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abstract = "The purpose of this study was to estimate the incidence density and prevalence of dengue virus infection in Australian travellers to Asia. We conducted a multi-centre prospective cohort study of Australian travellers over a 32-month period. We recruited 467 travellers (=16 years of age) from three travel clinics who intended to travel Asia, and 387 (82.9 ) of those travellers completed questionnaires and provide samples pre- and post-travel for serological testing for dengue virus infection. Demographic data, destination countries and history of vaccinations and flavivirus infections were obtained. Serological testing for dengue IgG and IgM by enzyme-linked immunosorbent assay (ELISA) (PanBio assay) was performed. Acute seroconversion for dengue infection was demonstrated in 1.0 of travellers, representing an incidence of 3.4 infections per 10,000 days of travel (95 confidence interval [CI]: 0.9?8.7). The seroprevalence of dengue infection was 4.4 and a greater number of prior trips to Asia was a predictor for dengue seroprevalence (p=0.019). All travellers experienced subclinical dengue infections and had travelled to India (n=3) and China (n=1). This significant attack rate of dengue infection can be used to advise prospective travellers to dengue-endemic countries.",

author = "I Ratnam and J Black and Karin Leder and Beverley-Ann Biggs and Elizabeth Matchett and Padiglione, {Alexander A} and Woolley, {Ian John} and T Panagiotidis and T Gheradin and L Pollissard and C Demont and C Luxemburger and Joseph Torresi",

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Ratnam, I, Black, J, Leder, K, Biggs, B-A, Matchett, E, Padiglione, AA, Woolley, IJ, Panagiotidis, T, Gheradin, T, Pollissard, L, Demont, C, Luxemburger, C & Torresi, J 2012, 'Incidence and seroprevalence of dengue virus infections in Australian travellers to Asia', European Journal of Clinical Microbiology and Infectious Diseases, vol. 31, no. 6, pp. 1203 - 1210. https://doi.org/10.1007/s10096-011-1429-1

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AU - Woolley, Ian John

AU - Panagiotidis, T

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AU - Demont, C

AU - Luxemburger, C

AU - Torresi, Joseph

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Incidence and seroprevalence of dengue virus infections in Australian travellers to Asia

Abstract

UN SDGs

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Improving knowledge regarding the burden of infection associated with water exposure and with international travel: addressing data gaps to improve policy and practice

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Incidence and seroprevalence of dengue virus infections in Australian travellers to Asia

Abstract

UN SDGs

Access to Document

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Improving knowledge regarding the burden of infection associated with water exposure and with international travel: addressing data gaps to improve policy and practice

Cite this