In vivo imaging: Shining a light on stem cells in the living animal

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4 Citations (Scopus)

Abstract

Stem cells are undifferentiated cells that play crucial roles during development, growth and regeneration. Traditionally, these cells have been primarily characterised by histology, cell sorting, cell culture and ex vivo methods. However, as stem cells interact in a complex environment within specific tissue niches, there has been increasing interest in examining their in vivo behaviours, particularly in response to injury. Advances in imaging technologies and genetic tools have converged to enable unprecedented access to the endogenous stem cell niche. In this Spotlight article, we highlight how in vivo imaging can probe a range of biological processes that relate to stem cell activity, behaviour and control.

Original languageEnglish
Article numberdev150441
Number of pages4
JournalDevelopment
Volume145
Issue number7
DOIs
Publication statusPublished - 1 Apr 2018

Keywords

  • Cell behaviour
  • In vivo imaging
  • Stem cell

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