In vivo characterization and numerical simulation of prostate properties for non-thermal irreversible electroporation ablation

Robert E Neal II; Jeremy Millar; Helen Kavnoudias; Peter Royce; Franklin Lawrence Rosenfeldt; Alan Pham; Ryan L Smith; Rafael V Davalos; Kenneth R Thomson

doi:10.1002/pros.22760

In vivo characterization and numerical simulation of prostate properties for non-thermal irreversible electroporation ablation

Robert E Neal II, Jeremy Millar, Helen Kavnoudias, Peter Royce, Franklin Lawrence Rosenfeldt, Alan Pham, Ryan L Smith, Rafael V Davalos, Kenneth R Thomson

Surgery Alfred Hospital

Research output: Contribution to journal › Article › Research › peer-review

111 Citations (Scopus)

Abstract

Irreversible electroporation (IRE) delivers brief electric pulses to attain non-thermal focal ablation that spares vasculature and other sensitive systems. It is a promising prostate cancer treatment due to sparing of the tissues associated with morbidity risk from conventional therapies. IRE effects depend on electric field strength and tissue properties. These characteristics are organ-dependent, affecting IRE treatment outcomes. This study characterizes the relevant properties to improve treatment planning and outcome predictions for IRE prostate cancer treatment.

Original language	English
Pages (from-to)	458 - 468
Number of pages	11
Journal	The Prostate
Volume	74
Issue number	5
DOIs	https://doi.org/10.1002/pros.22760
Publication status	Published - 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/pros.22760

Cite this

@article{d5274b517fe54e54a6ac29f041bb39d2,

title = "In vivo characterization and numerical simulation of prostate properties for non-thermal irreversible electroporation ablation",

abstract = "Irreversible electroporation (IRE) delivers brief electric pulses to attain non-thermal focal ablation that spares vasculature and other sensitive systems. It is a promising prostate cancer treatment due to sparing of the tissues associated with morbidity risk from conventional therapies. IRE effects depend on electric field strength and tissue properties. These characteristics are organ-dependent, affecting IRE treatment outcomes. This study characterizes the relevant properties to improve treatment planning and outcome predictions for IRE prostate cancer treatment.",

author = "{Neal II}, {Robert E} and Jeremy Millar and Helen Kavnoudias and Peter Royce and Rosenfeldt, {Franklin Lawrence} and Alan Pham and Smith, {Ryan L} and Davalos, {Rafael V} and Thomson, {Kenneth R}",

year = "2014",

doi = "10.1002/pros.22760",

language = "English",

volume = "74",

pages = "458 -- 468",

journal = "The Prostate",

issn = "0270-4137",

publisher = "John Wiley & Sons",

number = "5",

}

TY - JOUR

T1 - In vivo characterization and numerical simulation of prostate properties for non-thermal irreversible electroporation ablation

AU - Neal II, Robert E

AU - Millar, Jeremy

AU - Kavnoudias, Helen

AU - Royce, Peter

AU - Rosenfeldt, Franklin Lawrence

AU - Pham, Alan

AU - Smith, Ryan L

AU - Davalos, Rafael V

AU - Thomson, Kenneth R

PY - 2014

Y1 - 2014

N2 - Irreversible electroporation (IRE) delivers brief electric pulses to attain non-thermal focal ablation that spares vasculature and other sensitive systems. It is a promising prostate cancer treatment due to sparing of the tissues associated with morbidity risk from conventional therapies. IRE effects depend on electric field strength and tissue properties. These characteristics are organ-dependent, affecting IRE treatment outcomes. This study characterizes the relevant properties to improve treatment planning and outcome predictions for IRE prostate cancer treatment.

AB - Irreversible electroporation (IRE) delivers brief electric pulses to attain non-thermal focal ablation that spares vasculature and other sensitive systems. It is a promising prostate cancer treatment due to sparing of the tissues associated with morbidity risk from conventional therapies. IRE effects depend on electric field strength and tissue properties. These characteristics are organ-dependent, affecting IRE treatment outcomes. This study characterizes the relevant properties to improve treatment planning and outcome predictions for IRE prostate cancer treatment.

UR - http://onlinelibrary.wiley.com/doi/10.1002/pros.22760/pdf

U2 - 10.1002/pros.22760

DO - 10.1002/pros.22760

M3 - Article

SN - 0270-4137

VL - 74

SP - 458

EP - 468

JO - The Prostate

JF - The Prostate

IS - 5

ER -

In vivo characterization and numerical simulation of prostate properties for non-thermal irreversible electroporation ablation

Abstract

UN SDGs

Access to Document

Other files and links

Cite this