In vivo characterization and numerical simulation of prostate properties for non-thermal irreversible electroporation ablation

Robert E Neal II, Jeremy Millar, Helen Kavnoudias, Peter Royce, Franklin Lawrence Rosenfeldt, Alan Pham, Ryan L Smith, Rafael V Davalos, Kenneth R Thomson

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101 Citations (Scopus)

Abstract

Irreversible electroporation (IRE) delivers brief electric pulses to attain non-thermal focal ablation that spares vasculature and other sensitive systems. It is a promising prostate cancer treatment due to sparing of the tissues associated with morbidity risk from conventional therapies. IRE effects depend on electric field strength and tissue properties. These characteristics are organ-dependent, affecting IRE treatment outcomes. This study characterizes the relevant properties to improve treatment planning and outcome predictions for IRE prostate cancer treatment.
Original languageEnglish
Pages (from-to)458 - 468
Number of pages11
JournalThe Prostate
Volume74
Issue number5
DOIs
Publication statusPublished - 2014

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