Abstract
There is considerable interest in the derivation of neuronal cells from pluripotent stem cells (PSCs). Cells produced in this way have potential uses in the treatment of neurodegenerative diseases, drug discovery studies, or for basic research in neuroscience. Here, we describe protocols for the directed differentiation of forebrain GABAergic and midbrain dopaminergic neurons, using murine and human PSCs.
Original language | English |
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Title of host publication | Neural Stem Cell Assays |
Editors | Navjot Kaur, Mohan C Vemuri |
Place of Publication | Hoboken NJ USA |
Publisher | John Wiley & Sons |
Pages | 91-99 |
Number of pages | 9 |
ISBN (Electronic) | 9781118308295 |
ISBN (Print) | 9781118308257 |
DOIs | |
Publication status | Published - 30 Jan 2015 |
Keywords
- Directed differentiation
- Dopaminergic neurons
- GABAergic neurons
- Human pluripotent stem cells
- Mouse pluripotent stem cells
- Neural differentiation