In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism

Giannie Barsha; Katrina M. Mirabito Colafella; Sarah L. Walton; Tracey A. Gaspari; Iresha Spizzo; Anita A. Pinar; Lucinda M. Hilliard Krause; Robert E. Widdop; Chrishan S. Samuel; Kate M. Denton

doi:10.1161/HYPERTENSIONAHA.121.17164

In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism

Giannie Barsha, Katrina M. Mirabito Colafella, Sarah L. Walton, Tracey A. Gaspari, Iresha Spizzo, Anita A. Pinar, Lucinda M. Hilliard Krause, Robert E. Widdop, Chrishan S. Samuel, Kate M. Denton

Research output: Contribution to journal › Article › Research › peer-review

Abstract

[Figure: see text].

Original language	English
Pages (from-to)	128-137
Number of pages	10
Journal	Hypertension
Volume	78
Issue number	1
DOIs	https://doi.org/10.1161/HYPERTENSIONAHA.121.17164
Publication status	Published - Jul 2021

Keywords

aging
angiotensin II
cardiovascular disease
endothelium
menopause

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1161/HYPERTENSIONAHA.121.17164

Cite this

Barsha, G., Mirabito Colafella, K. M., Walton, S. L., Gaspari, T. A., Spizzo, I., Pinar, A. A., Hilliard Krause, L. M., Widdop, R. E., Samuel, C. S., & Denton, K. M. (2021). In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism. Hypertension, 78(1), 128-137. https://doi.org/10.1161/HYPERTENSIONAHA.121.17164

Barsha, Giannie ; Mirabito Colafella, Katrina M. ; Walton, Sarah L. ; Gaspari, Tracey A. ; Spizzo, Iresha ; Pinar, Anita A. ; Hilliard Krause, Lucinda M. ; Widdop, Robert E. ; Samuel, Chrishan S. ; Denton, Kate M. / In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism. In: Hypertension. 2021 ; Vol. 78, No. 1. pp. 128-137.

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title = "In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism",

abstract = "[Figure: see text].",

keywords = "aging, angiotensin II, cardiovascular disease, endothelium, menopause",

author = "Giannie Barsha and {Mirabito Colafella}, {Katrina M.} and Walton, {Sarah L.} and Gaspari, {Tracey A.} and Iresha Spizzo and Pinar, {Anita A.} and {Hilliard Krause}, {Lucinda M.} and Widdop, {Robert E.} and Samuel, {Chrishan S.} and Denton, {Kate M.}",

note = "Copyright: This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine",

year = "2021",

month = jul,

doi = "10.1161/HYPERTENSIONAHA.121.17164",

language = "English",

volume = "78",

pages = "128--137",

journal = "Hypertension",

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Barsha, G, Mirabito Colafella, KM , Walton, SL , Gaspari, TA, Spizzo, I, Pinar, AA, Hilliard Krause, LM , Widdop, RE , Samuel, CS & Denton, KM 2021, 'In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism', Hypertension, vol. 78, no. 1, pp. 128-137. https://doi.org/10.1161/HYPERTENSIONAHA.121.17164

In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism. / Barsha, Giannie; Mirabito Colafella, Katrina M.; Walton, Sarah L.; Gaspari, Tracey A.; Spizzo, Iresha; Pinar, Anita A.; Hilliard Krause, Lucinda M.; Widdop, Robert E.; Samuel, Chrishan S.; Denton, Kate M.

In: Hypertension, Vol. 78, No. 1, 07.2021, p. 128-137.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism

AU - Barsha, Giannie

AU - Mirabito Colafella, Katrina M.

AU - Walton, Sarah L.

AU - Gaspari, Tracey A.

AU - Spizzo, Iresha

AU - Pinar, Anita A.

AU - Hilliard Krause, Lucinda M.

AU - Widdop, Robert E.

AU - Samuel, Chrishan S.

AU - Denton, Kate M.

N1 - Copyright: This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine

PY - 2021/7

Y1 - 2021/7

N2 - [Figure: see text].

AB - [Figure: see text].

KW - aging

KW - angiotensin II

KW - cardiovascular disease

KW - endothelium

KW - menopause

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U2 - 10.1161/HYPERTENSIONAHA.121.17164

DO - 10.1161/HYPERTENSIONAHA.121.17164

M3 - Article

C2 - 33966450

AN - SCOPUS:85108025402

VL - 78

SP - 128

EP - 137

JO - Hypertension

JF - Hypertension

SN - 0194-911X

IS - 1

ER -

In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Targeting Prevention and Treatment of Hypertensive Cardiovascular Disease

Unravelling the aetiology of preeclampsia

Understanding the cardio-protective actions of the AT2R in females: Shifting gears between AT1 and AT2 receptor balance of function with relaxin.

Cite this

In Aged Females, the Enhanced Pressor Response to Angiotensin II Is Attenuated By Estrogen Replacement via an Angiotensin Type 2 Receptor-Mediated Mechanism

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Projects

Targeting Prevention and Treatment of Hypertensive Cardiovascular Disease

Unravelling the aetiology of preeclampsia

Understanding the cardio-protective actions of the AT2R in females: Shifting gears between AT1 and AT2 receptor balance of function with relaxin.

Cite this