Improving medication adherence in adult kidney transplantation (IMAKT): A pilot randomised controlled trial

Jac Kee Low; Elizabeth Manias; Kimberley Crawford; Rowan Walker; William R. Mulley; Nigel D. Toussaint; Michael Dooley; Elaine Kennedy; Catherine L. Smith; Michelle Nalder; Doris Yip; Allison Williams

doi:10.1038/s41598-019-44002-y

Improving medication adherence in adult kidney transplantation (IMAKT): A pilot randomised controlled trial

Jac Kee Low, Elizabeth Manias, Kimberley Crawford, Rowan Walker, William R. Mulley, Nigel D. Toussaint, Michael Dooley, Elaine Kennedy, Catherine L. Smith, Michelle Nalder, Doris Yip, Allison Williams

Research output: Contribution to journal › Article › Research › peer-review

31 Citations (Scopus)

Abstract

Resources to support long-term medication adherence in kidney transplantation are limited. This study aimed to determine the efficacy of an intervention designed for kidney transplant recipients to enhance medication adherence. A single-blind, multi-site, 12-month pilot randomised controlled trial was conducted at all five public hospitals providing adult kidney transplantation in Victoria, Australia. Participants were recruited at 4 to 6 weeks post-transplantation. Thirty-five participants were randomly assigned to a 3-month intervention, involving a face-to-face meeting (a medication review and a consumer-centred video) and health coaching every two weeks. Thirty-six were randomised to receive usual care. All participants were followed for nine months post-intervention. There were no differences in adherence between groups measured by Medication Event Monitoring System (MEMS), however, it was underutilised by 42% of participants. Based on the self-reported Basel Assessment of Adherence to Immunosuppressive Medications Scale (BAASIS

Original language	English
Article number	7734
Number of pages	8
Journal	Scientific Reports
Volume	9
Issue number	1
DOIs	https://doi.org/10.1038/s41598-019-44002-y
Publication status	Published - 22 May 2019

Keywords

end-stage renal disease
patient education

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10.1038/s41598-019-44002-y

280867819-oaFinal published version, 1.01 MB

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title = "Improving medication adherence in adult kidney transplantation (IMAKT): A pilot randomised controlled trial",

abstract = "Resources to support long-term medication adherence in kidney transplantation are limited. This study aimed to determine the efficacy of an intervention designed for kidney transplant recipients to enhance medication adherence. A single-blind, multi-site, 12-month pilot randomised controlled trial was conducted at all five public hospitals providing adult kidney transplantation in Victoria, Australia. Participants were recruited at 4 to 6 weeks post-transplantation. Thirty-five participants were randomly assigned to a 3-month intervention, involving a face-to-face meeting (a medication review and a consumer-centred video) and health coaching every two weeks. Thirty-six were randomised to receive usual care. All participants were followed for nine months post-intervention. There were no differences in adherence between groups measured by Medication Event Monitoring System (MEMS), however, it was underutilised by 42% of participants. Based on the self-reported Basel Assessment of Adherence to Immunosuppressive Medications Scale (BAASIS",

keywords = "end-stage renal disease, patient education",

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doi = "10.1038/s41598-019-44002-y",

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AU - Low, Jac Kee

AU - Manias, Elizabeth

AU - Crawford, Kimberley

AU - Walker, Rowan

AU - Mulley, William R.

AU - Toussaint, Nigel D.

AU - Dooley, Michael

AU - Kennedy, Elaine

AU - Smith, Catherine L.

AU - Nalder, Michelle

AU - Yip, Doris

AU - Williams, Allison

PY - 2019/5/22

Y1 - 2019/5/22

N2 - Resources to support long-term medication adherence in kidney transplantation are limited. This study aimed to determine the efficacy of an intervention designed for kidney transplant recipients to enhance medication adherence. A single-blind, multi-site, 12-month pilot randomised controlled trial was conducted at all five public hospitals providing adult kidney transplantation in Victoria, Australia. Participants were recruited at 4 to 6 weeks post-transplantation. Thirty-five participants were randomly assigned to a 3-month intervention, involving a face-to-face meeting (a medication review and a consumer-centred video) and health coaching every two weeks. Thirty-six were randomised to receive usual care. All participants were followed for nine months post-intervention. There were no differences in adherence between groups measured by Medication Event Monitoring System (MEMS), however, it was underutilised by 42% of participants. Based on the self-reported Basel Assessment of Adherence to Immunosuppressive Medications Scale (BAASIS

AB - Resources to support long-term medication adherence in kidney transplantation are limited. This study aimed to determine the efficacy of an intervention designed for kidney transplant recipients to enhance medication adherence. A single-blind, multi-site, 12-month pilot randomised controlled trial was conducted at all five public hospitals providing adult kidney transplantation in Victoria, Australia. Participants were recruited at 4 to 6 weeks post-transplantation. Thirty-five participants were randomly assigned to a 3-month intervention, involving a face-to-face meeting (a medication review and a consumer-centred video) and health coaching every two weeks. Thirty-six were randomised to receive usual care. All participants were followed for nine months post-intervention. There were no differences in adherence between groups measured by Medication Event Monitoring System (MEMS), however, it was underutilised by 42% of participants. Based on the self-reported Basel Assessment of Adherence to Immunosuppressive Medications Scale (BAASIS

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Improving medication adherence in adult kidney transplantation (IMAKT): A pilot randomised controlled trial

Abstract

Keywords

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Improving medicine adherence in kidney transplantation

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Improving medication adherence in adult kidney transplantation (IMAKT): A pilot randomised controlled trial

Abstract

Keywords

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Improving medicine adherence in kidney transplantation

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