Improving medication adherence in adult kidney transplantation (IMAKT)

A pilot randomised controlled trial

Jac Kee Low, Elizabeth Manias, Kimberley Crawford, Rowan Walker, William R. Mulley, Nigel D. Toussaint, Michael Dooley, Elaine Kennedy, Catherine L. Smith, Michelle Nalder, Doris Yip, Allison Williams

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Resources to support long-term medication adherence in kidney transplantation are limited. This study aimed to determine the efficacy of an intervention designed for kidney transplant recipients to enhance medication adherence. A single-blind, multi-site, 12-month pilot randomised controlled trial was conducted at all five public hospitals providing adult kidney transplantation in Victoria, Australia. Participants were recruited at 4 to 6 weeks post-transplantation. Thirty-five participants were randomly assigned to a 3-month intervention, involving a face-to-face meeting (a medication review and a consumer-centred video) and health coaching every two weeks. Thirty-six were randomised to receive usual care. All participants were followed for nine months post-intervention. There were no differences in adherence between groups measured by Medication Event Monitoring System (MEMS), however, it was underutilised by 42% of participants. Based on the self-reported Basel Assessment of Adherence to Immunosuppressive Medications Scale (BAASIS

Original languageEnglish
Article number7734
Number of pages8
JournalScientific Reports
Volume9
Issue number1
DOIs
Publication statusPublished - 22 May 2019

Keywords

  • end-stage renal disease
  • patient education

Cite this

Low, Jac Kee ; Manias, Elizabeth ; Crawford, Kimberley ; Walker, Rowan ; Mulley, William R. ; Toussaint, Nigel D. ; Dooley, Michael ; Kennedy, Elaine ; Smith, Catherine L. ; Nalder, Michelle ; Yip, Doris ; Williams, Allison. / Improving medication adherence in adult kidney transplantation (IMAKT) : A pilot randomised controlled trial. In: Scientific Reports. 2019 ; Vol. 9, No. 1.
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abstract = "Resources to support long-term medication adherence in kidney transplantation are limited. This study aimed to determine the efficacy of an intervention designed for kidney transplant recipients to enhance medication adherence. A single-blind, multi-site, 12-month pilot randomised controlled trial was conducted at all five public hospitals providing adult kidney transplantation in Victoria, Australia. Participants were recruited at 4 to 6 weeks post-transplantation. Thirty-five participants were randomly assigned to a 3-month intervention, involving a face-to-face meeting (a medication review and a consumer-centred video) and health coaching every two weeks. Thirty-six were randomised to receive usual care. All participants were followed for nine months post-intervention. There were no differences in adherence between groups measured by Medication Event Monitoring System (MEMS), however, it was underutilised by 42{\%} of participants. Based on the self-reported Basel Assessment of Adherence to Immunosuppressive Medications Scale (BAASIS",
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Improving medication adherence in adult kidney transplantation (IMAKT) : A pilot randomised controlled trial. / Low, Jac Kee; Manias, Elizabeth; Crawford, Kimberley; Walker, Rowan; Mulley, William R.; Toussaint, Nigel D.; Dooley, Michael; Kennedy, Elaine; Smith, Catherine L.; Nalder, Michelle; Yip, Doris; Williams, Allison.

In: Scientific Reports, Vol. 9, No. 1, 7734, 22.05.2019.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Low, Jac Kee

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AU - Mulley, William R.

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AU - Dooley, Michael

AU - Kennedy, Elaine

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AU - Williams, Allison

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