Abstract
Melt electrospinning can be used to produce fibres within the micro to nano scale with a deposition in a manner in-line with conventional 3D printing technology’s [1]. Technical issues such as charge build up in subsequent layers lead to limitations in the precision of fibre deposition as the number of layers increases. Polycaprolactone (PCL) is a polyester with a wellestablished history as a scaffold material for bone tissue engineering [2]. It is biocompatible, easy to shape and mechanically suitable for bone defects. Bioactive glasses are ceramic materials which are known to stimulate osteogenic differentiation [3]. The combination of PCL and bioactive glasses present the possibility to develop osteogenic scaffolds with a high degree of control of laydown using melt electrospinning [4]. This work develops the potential of melt electrospinning as a scaffold fabrication technique for tissue engineering non-load bearing bone defects by both developing techniques for improcing fibre laydown introducing osteogenic factors.
Original language | English |
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Title of host publication | 5th International Conference on Biomedical Engineering in Vietnam |
Editors | Vo Van Toi, Tran Ha Lien Phuong |
Publisher | Springer |
Pages | 125-128 |
Number of pages | 4 |
ISBN (Electronic) | 9783319117751 |
DOIs | |
Publication status | Published - 1 Jan 2015 |
Externally published | Yes |
Event | International Conference on the Development of Biomedical Engineering in Vietnam 2014 - Ho Chi Minh City, Vietnam Duration: 16 Jun 2014 → 18 Jun 2014 Conference number: 5th |
Publication series
Name | IFMBE Proceedings |
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Volume | 46 |
ISSN (Print) | 1680-0737 |
Conference
Conference | International Conference on the Development of Biomedical Engineering in Vietnam 2014 |
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Country/Territory | Vietnam |
City | Ho Chi Minh City |
Period | 16/06/14 → 18/06/14 |
Keywords
- Bioactive Glass
- Electrospinning
- Polycaprolactone