Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop

J H Sun, James C Whisstock, Patrick Harriott, Brian Walker, Andrea J Novak, Philip E Thompson, A I Smith, Phillip I Bird

Research output: Contribution to journalArticleResearchpeer-review

64 Citations (Scopus)
Original languageEnglish
Pages (from-to)15177 - 15184
Number of pages8
JournalJournal of Biological Chemistry
Volume276
Issue number18
Publication statusPublished - 2001

Cite this

@article{270882884a0f4f2ab1abd78e2580620b,
title = "Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop",
author = "Sun, {J H} and Whisstock, {James C} and Patrick Harriott and Brian Walker and Novak, {Andrea J} and Thompson, {Philip E} and Smith, {A I} and Bird, {Phillip I}",
year = "2001",
language = "English",
volume = "276",
pages = "15177 -- 15184",
journal = "Journal of Biological Chemistry",
issn = "1083-351X",
publisher = "American Society for Biochemistry and Molecular Biology",
number = "18",

}

Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop. / Sun, J H; Whisstock, James C; Harriott, Patrick; Walker, Brian; Novak, Andrea J; Thompson, Philip E; Smith, A I; Bird, Phillip I.

In: Journal of Biological Chemistry, Vol. 276, No. 18, 2001, p. 15177 - 15184.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop

AU - Sun, J H

AU - Whisstock, James C

AU - Harriott, Patrick

AU - Walker, Brian

AU - Novak, Andrea J

AU - Thompson, Philip E

AU - Smith, A I

AU - Bird, Phillip I

PY - 2001

Y1 - 2001

M3 - Article

VL - 276

SP - 15177

EP - 15184

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 1083-351X

IS - 18

ER -