Impaired blood pressure control in children with obstructive sleep apnea

Lisa Mary Walter, Stephanie Yiallourou, Anna Vlahandonis, Scott Sands, Candice Johnson, Gillian Michelle Nixon, Margot J Davey, John A Trinder, Adrian Mark Walker, Rosemary Sylvia Claire Horne

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36 Citations (Scopus)


BACKGROUND: Obstructive sleep apnea (OSA) in adults has been associated with hypertension, low baroreflex sensitivity (BRS), a delayed heart rate response to changing blood pressure (heart period delay [HPD]), and increased blood pressure variability (BPV). Poor BRS may contribute to hypertension by impairing the control of blood pressure (BP), with increased BPV and HPD. Although children with OSA have elevated BP, there are scant data on BRS, BPV, or HPD in this group. METHODS: 105 children ages 7-12 years referred for assessment of OSA and 36 nonsnoring controls were studied. Overnight polysomnography (PSG) was performed with continuous BP monitoring. Subjects were assigned to groups according to their obstructive apnea-hypopnea index (OAHI): primary snoring (PS) (OAHI 1- 5events/h). BRS and HPD were calculated using cross spectral analysis and BPV using power spectral analysis. RESULTS: Subjects with OSA had significantly lower BRS (p
Original languageEnglish
Pages (from-to)858 - 866
Number of pages9
JournalSleep Medicine
Issue number9
Publication statusPublished - 2013

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