TY - JOUR
T1 - Impacts of High Concentration, Medium Duration Coal Mine Fire Related PM2.5 on Cancer Incidence
T2 - 5-Year Follow-Up of the Hazelwood Health Study
AU - Yu, Pei
AU - Guo, Yuming
AU - Gao, Caroline X.
AU - Dimitriadis, Christina
AU - Ikin, Jillian F.
AU - Del Monaco, Anthony
AU - Brown, David
AU - Sim, Malcolm R.
AU - Abramson, Michael J.
N1 - Funding Information:
We thank participants in the HHS Adult Survey, Victorian Cancer Registry. The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: PY was supported by the China Scholarship Council (201906210065). YG was supported by a Career Development Fellowship of the Australian National Health and Medical Research Council (APP1163693). The Hazelwood Health Study is funded by the Victorian Department of Health, however this paper presents the views of the authors and does not represent the views of the Department.
Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: PY was supported by the China Scholarship Council (201906210065). YG was supported by a Career Development Fellowship of the Australian National Health and Medical Research Council (APP1163693). The Hazelwood Health Study is funded by the Victorian Department of Health, however this paper presents the views of the authors and does not represent the views of the Department.
Publisher Copyright:
© The Author(s) 2021.
PY - 2021
Y1 - 2021
N2 - No studies have investigated the cancer outcomes from high level medium duration coal mine fire fine particulate matter ⩽2.5 µm in diameter (PM2.5) exposure. We included 2208 Morwell residents (exposed) and 646 Sale residents (unexposed) who participated in the Hazelwood Health Study Adult Survey. Competing risk regression models were used to evaluate relationships between coal mine fire exposure and cancer incidence, adjusting for known confounders. There were 137 cancers in the exposed and 27 in the unexposed over 14 849 person-years of follow-up. A higher risk of cancer incidence was observed for Morwell participants (HR = 1.67 [95% CI 1.05-2.67]), but no evidence to suggest associations between PM2.5 exposure and incidence of all cancers (HR = 1.02 [95% CI 0.91-1.13]), or site-specific cancers. There is no strong evidence that exposure to high concentrations of mine fire-related PM2.5 over a prolonged period could explain the higher risk in exposed population in this study.
AB - No studies have investigated the cancer outcomes from high level medium duration coal mine fire fine particulate matter ⩽2.5 µm in diameter (PM2.5) exposure. We included 2208 Morwell residents (exposed) and 646 Sale residents (unexposed) who participated in the Hazelwood Health Study Adult Survey. Competing risk regression models were used to evaluate relationships between coal mine fire exposure and cancer incidence, adjusting for known confounders. There were 137 cancers in the exposed and 27 in the unexposed over 14 849 person-years of follow-up. A higher risk of cancer incidence was observed for Morwell participants (HR = 1.67 [95% CI 1.05-2.67]), but no evidence to suggest associations between PM2.5 exposure and incidence of all cancers (HR = 1.02 [95% CI 0.91-1.13]), or site-specific cancers. There is no strong evidence that exposure to high concentrations of mine fire-related PM2.5 over a prolonged period could explain the higher risk in exposed population in this study.
KW - cancer incidence
KW - Coal mine fire smoke
KW - data linkage cohort
KW - fine particulate matter
KW - Hazelwood Health Study
UR - http://www.scopus.com/inward/record.url?scp=85119520157&partnerID=8YFLogxK
U2 - 10.1177/11786302211059722
DO - 10.1177/11786302211059722
M3 - Article
C2 - 34819732
AN - SCOPUS:85119520157
SN - 1178-6302
VL - 15
SP - 1
EP - 4
JO - Environmental Health Insights
JF - Environmental Health Insights
ER -
