Impacto dos lipídios plasmáticos no controle glicêmico e sua influência no risco cardiometabólico em pacientes obesos mórbidos

Translated title of the contribution: Impact of plasmatic lipids in glycemic control and its influence in the cardiometabolic risk in morbidly obese subjects

Ary Serpa Neto, Felipe Martin Bianco Rossi, Rodrigo Dal Moro Amarante, Nara Alves Buriti, Marçal Rossi

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

Objectives: To evaluate whether biochemical parameters are associated with a good glycemic control and to identify the occurrence of cardiometabolic risk variables. Material and methods: One hundred forty Brazilians were evaluated. The subjects were characterized with regard to glycemic control as good, fair and poor and were divided into tertiles by TG and HbA1c. We use the ROC curve to determine which variables were predicted of poor glycemic control and the factor analyses to identify the domains that segregated among the risk variables. Results: Fasting glucose and insulin levels, TG level, VLDL-C and HOMA-IR increased significantly across HbA1c tertiles. The best marker for identification of poor glycemic control was triglycerides. The presence of cardiometabolic abnormalities did not alter the glycemic control, but HOMA-IR was significantly higher in subjects with abnormalities. Conclusion: The use of TG levels offers a reasonable degree of clinical utility. In morbidly obese subjects insulin resistance is associated with individual cardiometabolic factors.

Original languagePortuguese
Pages (from-to)747-754
Number of pages8
JournalArquivos Brasileiros de Endocrinologia e Metabologia
Volume53
Issue number6
DOIs
Publication statusPublished - Aug 2009
Externally publishedYes

Keywords

  • Bariatric surgery
  • Blood glucose
  • Diabetes mellitus
  • Obesity

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