Impact of early prophylactic feeding on long term tube dependency outcomes in patients with head and neck cancer

Teresa Brown, Merrilyn Banks, Brett G.M. Hughes, Charles Lin, Lizbeth M. Kenny, Judith D. Bauer

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Abstract

Objectives Prophylactic gastrostomy tube (PGT) is frequently used in patients with head and neck cancer (HNSCC). There are concerns this leads to tube dependency but this phenomena is not well defined. This study aimed to determine whether early feeding via PGT impacted on longer term tube feeding outcomes. Materials and methods Patients with HNSCC with PGT were observed monthly post-treatment regarding tube use and time to removal up to twelve months. Patients were from a randomised controlled trial comparing an early feeding intervention via the PGT (n = 57) versus usual care which commenced feeding when clinically indicated (n = 67). Results Patient characteristics; male (88%), mean age 60 ± 10.1 years, oropharyngeal tumours (76%), receiving chemoradiotherapy (82%). Tubes were used by 87% (108/124) on completion of treatment and 66% (83/124) one month post. No differences in tube use between groups at any time point or tube removal rates over 12 months (p = 0.181). In patients free of disease (n = 99), the intervention had higher tube use at 4 months (p = 0.003) and slower removal rates (p = 0.047). Overall ten patients had their tube in-situ at 12 months (8%) but five were awaiting removal (4% true dependency rate). Of the five patients legitimately using the tube, only one (<1%) was from severe dysphagia post definitive chemoradiotherapy. Conclusion PGT use is high in the acute phase post-treatment. Encouraging early use may prolong time to tube removal but it does not increase long term dependency rates beyond four months post treatment. Monitoring tube use is important to prevent over-estimation of dependency rates. Clinical trial registration This trial has been registered in the Australian New Zealand Clinical Trials registry as ACTRN12612000579897. Available at http://www.anzctr.org.au.

Original languageEnglish
Pages (from-to)17-25
Number of pages9
JournalOral Oncology
Volume72
DOIs
Publication statusPublished - Sept 2017
Externally publishedYes

Keywords

  • Chemoradiotherapy
  • Dysphagia
  • Enteral feeding
  • Gastrostomy
  • Head and neck cancer
  • Oral cancer
  • Post treatment
  • Tube dependency

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