Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program

Roberto Diletti; Hector M Garcia-Garcia; Christos V Bourantas; Nicolas M Van Mieghem; Robert-Jan van Geuns; Takashi Muramatsu; Yao-Jun Zhang; Laura Mauri; Jorge A Belardi; Sigmund Silber; Petr Widimsky; Martin B Leon; Stephan Windecker; Ian T Meredith; Franz-Josef Neumann; Alan C Yeung; Shigeru Saito; Minglei Liu; Frank van Leeuwen; Patrick W Serruys

doi:10.1002/ccd.25828

Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program

Roberto Diletti, Hector M Garcia-Garcia, Christos V Bourantas, Nicolas M Van Mieghem, Robert-Jan van Geuns, Takashi Muramatsu, Yao-Jun Zhang, Laura Mauri, Jorge A Belardi, Sigmund Silber, Petr Widimsky, Martin B Leon, Stephan Windecker, Ian T Meredith, Franz-Josef Neumann, Alan C Yeung, Shigeru Saito, Minglei Liu, Frank van Leeuwen, Patrick W Serruys

School of Clinical Sciences at Monash Health

Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)

Abstract

An increased body mass index (BMI) is associated with a high risk of cardiovascular disease and reduction in life expectancy. However, several studies reported improved clinical outcomes in obese patients treated for cardiovascular diseases. The aim of the present study is to investigate the impact of BMI on long-term clinical outcomes after implantation of zotarolimus eluting stents.METHODS: Individual patient data were pooled from the RESOLUTE Clinical Program comprising five trials worldwide. The study population was sorted according to BMI tertiles and clinical outcomes were evaluated at 2-year follow-up.

Original language	English
Pages (from-to)	952 - 958
Number of pages	7
Journal	Catheterization and Cardiovascular Interventions
Volume	85
Issue number	6
DOIs	https://doi.org/10.1002/ccd.25828
Publication status	Published - 2015

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10.1002/ccd.25828

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Diletti, R., Garcia-Garcia, H. M., Bourantas, C. V., Van Mieghem, N. M., van Geuns, R-J., Muramatsu, T., Zhang, Y-J., Mauri, L., Belardi, J. A., Silber, S., Widimsky, P., Leon, M. B., Windecker, S., Meredith, I. T., Neumann, F-J., Yeung, A. C., Saito, S., Liu, M., van Leeuwen, F., & Serruys, P. W. (2015). Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program. Catheterization and Cardiovascular Interventions, 85(6), 952 - 958. https://doi.org/10.1002/ccd.25828

@article{7e57ac0d014f46d198f048a455a5f7f5,

title = "Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program",

abstract = "An increased body mass index (BMI) is associated with a high risk of cardiovascular disease and reduction in life expectancy. However, several studies reported improved clinical outcomes in obese patients treated for cardiovascular diseases. The aim of the present study is to investigate the impact of BMI on long-term clinical outcomes after implantation of zotarolimus eluting stents.METHODS: Individual patient data were pooled from the RESOLUTE Clinical Program comprising five trials worldwide. The study population was sorted according to BMI tertiles and clinical outcomes were evaluated at 2-year follow-up.",

author = "Roberto Diletti and Garcia-Garcia, {Hector M} and Bourantas, {Christos V} and {Van Mieghem}, {Nicolas M} and {van Geuns}, Robert-Jan and Takashi Muramatsu and Yao-Jun Zhang and Laura Mauri and Belardi, {Jorge A} and Sigmund Silber and Petr Widimsky and Leon, {Martin B} and Stephan Windecker and Meredith, {Ian T} and Franz-Josef Neumann and Yeung, {Alan C} and Shigeru Saito and Minglei Liu and {van Leeuwen}, Frank and Serruys, {Patrick W}",

year = "2015",

doi = "10.1002/ccd.25828",

language = "English",

volume = "85",

pages = "952 -- 958",

journal = "Catheterization and Cardiovascular Interventions",

issn = "1522-1946",

publisher = "Wiley-Blackwell",

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Diletti, R, Garcia-Garcia, HM, Bourantas, CV, Van Mieghem, NM, van Geuns, R-J, Muramatsu, T, Zhang, Y-J, Mauri, L, Belardi, JA, Silber, S, Widimsky, P, Leon, MB, Windecker, S, Meredith, IT, Neumann, F-J, Yeung, AC, Saito, S, Liu, M, van Leeuwen, F & Serruys, PW 2015, 'Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program', Catheterization and Cardiovascular Interventions, vol. 85, no. 6, pp. 952 - 958. https://doi.org/10.1002/ccd.25828

Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program. / Diletti, Roberto; Garcia-Garcia, Hector M; Bourantas, Christos V et al.

In: Catheterization and Cardiovascular Interventions, Vol. 85, No. 6, 2015, p. 952 - 958.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program

AU - Diletti, Roberto

AU - Garcia-Garcia, Hector M

AU - Bourantas, Christos V

AU - Van Mieghem, Nicolas M

AU - van Geuns, Robert-Jan

AU - Muramatsu, Takashi

AU - Zhang, Yao-Jun

AU - Mauri, Laura

AU - Belardi, Jorge A

AU - Silber, Sigmund

AU - Widimsky, Petr

AU - Leon, Martin B

AU - Windecker, Stephan

AU - Meredith, Ian T

AU - Neumann, Franz-Josef

AU - Yeung, Alan C

AU - Saito, Shigeru

AU - Liu, Minglei

AU - van Leeuwen, Frank

AU - Serruys, Patrick W

PY - 2015

Y1 - 2015

N2 - An increased body mass index (BMI) is associated with a high risk of cardiovascular disease and reduction in life expectancy. However, several studies reported improved clinical outcomes in obese patients treated for cardiovascular diseases. The aim of the present study is to investigate the impact of BMI on long-term clinical outcomes after implantation of zotarolimus eluting stents.METHODS: Individual patient data were pooled from the RESOLUTE Clinical Program comprising five trials worldwide. The study population was sorted according to BMI tertiles and clinical outcomes were evaluated at 2-year follow-up.

AB - An increased body mass index (BMI) is associated with a high risk of cardiovascular disease and reduction in life expectancy. However, several studies reported improved clinical outcomes in obese patients treated for cardiovascular diseases. The aim of the present study is to investigate the impact of BMI on long-term clinical outcomes after implantation of zotarolimus eluting stents.METHODS: Individual patient data were pooled from the RESOLUTE Clinical Program comprising five trials worldwide. The study population was sorted according to BMI tertiles and clinical outcomes were evaluated at 2-year follow-up.

UR - http://onlinelibrary.wiley.com/doi/10.1002/ccd.25828/pdf

U2 - 10.1002/ccd.25828

DO - 10.1002/ccd.25828

M3 - Article

VL - 85

SP - 952

EP - 958

JO - Catheterization and Cardiovascular Interventions

JF - Catheterization and Cardiovascular Interventions

SN - 1522-1946

IS - 6

ER -

Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program

Abstract

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