Impact of body mass index on long-term clinical outcomes after second-generation drug eluting stent implantation: Insights from the international global RESOLUTE program

Roberto Diletti, Hector M Garcia-Garcia, Christos V Bourantas, Nicolas M Van Mieghem, Robert-Jan van Geuns, Takashi Muramatsu, Yao-Jun Zhang, Laura Mauri, Jorge A Belardi, Sigmund Silber, Petr Widimsky, Martin B Leon, Stephan Windecker, Ian T Meredith, Franz-Josef Neumann, Alan C Yeung, Shigeru Saito, Minglei Liu, Frank van Leeuwen, Patrick W Serruys

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8 Citations (Scopus)

Abstract

An increased body mass index (BMI) is associated with a high risk of cardiovascular disease and reduction in life expectancy. However, several studies reported improved clinical outcomes in obese patients treated for cardiovascular diseases. The aim of the present study is to investigate the impact of BMI on long-term clinical outcomes after implantation of zotarolimus eluting stents.METHODS: Individual patient data were pooled from the RESOLUTE Clinical Program comprising five trials worldwide. The study population was sorted according to BMI tertiles and clinical outcomes were evaluated at 2-year follow-up.
Original languageEnglish
Pages (from-to)952 - 958
Number of pages7
JournalCatheterization and Cardiovascular Interventions
Volume85
Issue number6
DOIs
Publication statusPublished - 2015

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