Immunosuppression increases latent infection of brain by JC polyomavirus

Julianne Bayliss, Tania Karasoulos, Scott Bowden, Ivana Glogowski, Catriona Ann McLean

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Abstract

Brain and kidney tissue from 138 non-PML patients (78 immunocompetent; 60 immunosuppressed) was assessed for JCV large T (LT) and viral protein (VP)1 DNA with nested PCR. Immunohistochemistry was performed to detect presence of JCV protein. Autopsy findings were reviewed and all brains underwent neuropathological examination
Original languageEnglish
Pages (from-to)362 - 367
Number of pages6
JournalPathology
Volume43
Issue number4
DOIs
Publication statusPublished - 2011

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