Immunodeficiencies affecting cellular and humoral immunity

Zahra Chavoshzadeh; Sepideh Darougar; Tooba Momen; Hossein Esmaeilzadeh; Hassan Abolhassani; Taher Cheraghi; Mirjam van der Burg; Menno van Zelm

doi:10.1016/B978-0-12-821028-4.00010-5

Immunodeficiencies affecting cellular and humoral immunity

Zahra Chavoshzadeh, Sepideh Darougar, Tooba Momen, Hossein Esmaeilzadeh, Hassan Abolhassani, Taher Cheraghi, Mirjam van der Burg, Menno van Zelm

Immunology Alfred Hospital

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

3 Citations (Scopus)

Abstract

Combined immunodeficiencies (CIDs) are the result of defective development or function of T cells. As the most severe form of primary immunodeficiency disorders (PID), CIDs are characterized by a susceptibility to infection, particularly from opportunistic organisms, which leads to severe morbidity and mortality. A subpopulation of patients has additional syndromic features caused by the function of the affected gene beyond the immune system. In this chapter, we will focus on nonsyndromic CIDs.

Original language	English
Title of host publication	Inborn Errors of Immunity
Subtitle of host publication	A Practical Guide
Editors	Asghar Aghamohammadi, Hassan Abolhassani
Place of Publication	London UK
Publisher	Elsevier
Chapter	2
Pages	9-39
Number of pages	31
ISBN (Electronic)	9780128210284
ISBN (Print)	9780128231890
DOIs	https://doi.org/10.1016/B978-0-12-821028-4.00010-5
Publication status	Published - 2021

Keywords

Clinical manifestations
Combined immunodeficiency
Diagnosis
Nonsyndromic
Pathogenesis
Primary immunodeficiency disorders

Access to Document

10.1016/B978-0-12-821028-4.00010-5

Cite this

@inbook{8df515eb415c41db982c129dfe815576,

title = "Immunodeficiencies affecting cellular and humoral immunity",

abstract = "Combined immunodeficiencies (CIDs) are the result of defective development or function of T cells. As the most severe form of primary immunodeficiency disorders (PID), CIDs are characterized by a susceptibility to infection, particularly from opportunistic organisms, which leads to severe morbidity and mortality. A subpopulation of patients has additional syndromic features caused by the function of the affected gene beyond the immune system. In this chapter, we will focus on nonsyndromic CIDs.",

keywords = "Clinical manifestations, Combined immunodeficiency, Diagnosis, Nonsyndromic, Pathogenesis, Primary immunodeficiency disorders",

author = "Zahra Chavoshzadeh and Sepideh Darougar and Tooba Momen and Hossein Esmaeilzadeh and Hassan Abolhassani and Taher Cheraghi and {van der Burg}, Mirjam and {van Zelm}, Menno",

year = "2021",

doi = "10.1016/B978-0-12-821028-4.00010-5",

language = "English",

isbn = "9780128231890",

pages = "9--39",

editor = "Asghar Aghamohammadi and Hassan Abolhassani",

booktitle = "Inborn Errors of Immunity",

publisher = "Elsevier",

address = "Netherlands",

}

TY - CHAP

T1 - Immunodeficiencies affecting cellular and humoral immunity

AU - Chavoshzadeh, Zahra

AU - Darougar, Sepideh

AU - Momen, Tooba

AU - Esmaeilzadeh, Hossein

AU - Abolhassani, Hassan

AU - Cheraghi, Taher

AU - van der Burg, Mirjam

AU - van Zelm, Menno

PY - 2021

Y1 - 2021

N2 - Combined immunodeficiencies (CIDs) are the result of defective development or function of T cells. As the most severe form of primary immunodeficiency disorders (PID), CIDs are characterized by a susceptibility to infection, particularly from opportunistic organisms, which leads to severe morbidity and mortality. A subpopulation of patients has additional syndromic features caused by the function of the affected gene beyond the immune system. In this chapter, we will focus on nonsyndromic CIDs.

AB - Combined immunodeficiencies (CIDs) are the result of defective development or function of T cells. As the most severe form of primary immunodeficiency disorders (PID), CIDs are characterized by a susceptibility to infection, particularly from opportunistic organisms, which leads to severe morbidity and mortality. A subpopulation of patients has additional syndromic features caused by the function of the affected gene beyond the immune system. In this chapter, we will focus on nonsyndromic CIDs.

KW - Clinical manifestations

KW - Combined immunodeficiency

KW - Diagnosis

KW - Nonsyndromic

KW - Pathogenesis

KW - Primary immunodeficiency disorders

UR - http://www.scopus.com/inward/record.url?scp=85137457980&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-821028-4.00010-5

DO - 10.1016/B978-0-12-821028-4.00010-5

M3 - Chapter (Book)

AN - SCOPUS:85137457980

SN - 9780128231890

SP - 9

EP - 39

BT - Inborn Errors of Immunity

A2 - Aghamohammadi, Asghar

A2 - Abolhassani, Hassan

PB - Elsevier

CY - London UK

ER -

Immunodeficiencies affecting cellular and humoral immunity

Abstract

Keywords

Access to Document

Other files and links

Cite this