Immune-mediated cytopenias in human immunodeficiency virus: The first reported case of idiopathic aplastic anaemia successfully treated with immunosuppression

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Abstract

Although isolated cytopenias are relatively common in human immunodeficiency virus (HIV), the incidence of aplastic anaemia is extremely rare. We report here the first case of a HIV-infected patient who developed severe idiopathic aplastic anaemia, and who was safely and effectively treated with anti-thymocyte globulin and cyclosporin. We briefly review immune-mediated cytopenias in HIV, including their frequency, pathophysiology and management strategies. ? 2013 Royal Australasian College of Physicians.
Original languageEnglish
Pages (from-to)452 - 455
Number of pages4
JournalInternal Medicine Journal
Volume43
Issue number4
DOIs
Publication statusPublished - 2013

Cite this

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title = "Immune-mediated cytopenias in human immunodeficiency virus: The first reported case of idiopathic aplastic anaemia successfully treated with immunosuppression",
abstract = "Although isolated cytopenias are relatively common in human immunodeficiency virus (HIV), the incidence of aplastic anaemia is extremely rare. We report here the first case of a HIV-infected patient who developed severe idiopathic aplastic anaemia, and who was safely and effectively treated with anti-thymocyte globulin and cyclosporin. We briefly review immune-mediated cytopenias in HIV, including their frequency, pathophysiology and management strategies. ? 2013 Royal Australasian College of Physicians.",
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AB - Although isolated cytopenias are relatively common in human immunodeficiency virus (HIV), the incidence of aplastic anaemia is extremely rare. We report here the first case of a HIV-infected patient who developed severe idiopathic aplastic anaemia, and who was safely and effectively treated with anti-thymocyte globulin and cyclosporin. We briefly review immune-mediated cytopenias in HIV, including their frequency, pathophysiology and management strategies. ? 2013 Royal Australasian College of Physicians.

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