Immune Hemolysis after an ABO mismatched renal transplant

A. C. PERKINS, V. L. RICHARDS, J. GIBSON, D. E. JOSHUA, J. R. JOHNSON, H. KRONENBERG

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Abstract

We describe a case of immune hemolysis due to anti‐B occurring in a blood group B patient 16 days after a cadaveric renal transplantation from a blood group O donor. Transfusional support was initially required and the direct antiglobulin test (DAT) remained positive for 80 days. Cyclosporin A (CSA), which was used for rejection prophylaxis in this case, has unique immunosuppressive capabilities which protects transplanted organs from rejection, but which might permit this type of ‘graft versus host’ reaction.

Original languageEnglish
Pages (from-to)345-346
Number of pages2
JournalAustralian and New Zealand Journal of Medicine
Volume19
Issue number4
DOIs
Publication statusPublished - 1989
Externally publishedYes

Keywords

  • Auto‐anti‐B
  • cyclosporin A.
  • renal transplantation

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