Imaging of the posttherapeutic brain

Bruno A. Telles, Francesco D'Amore, Alexander Lerner, Meng Law, Mark S. Shiroishi

Research output: Contribution to journalReview ArticleOtherpeer-review

9 Citations (Scopus)


This review covers important topics relating to the imaging evaluation of glioblastoma multiforme after therapy. An overview of the MacDonald and Response Assessment in Neuro-Oncology criteria as well as important questions and limitations regarding their use are provided. Pseudoprogression and pseudoresponse as well as the use of advanced magnetic resonance imaging techniques such as perfusion, diffusion, and spectroscopy in the evaluation of the posttherapeutic brain are also reviewed.

Original languageEnglish
Pages (from-to)147-154
Number of pages8
JournalTopics in Magnetic Resonance Imaging
Issue number3
Publication statusPublished - 1 Jan 2015
Externally publishedYes


  • diffusion MRI
  • glioblastoma multiforme
  • high-grade glioma
  • imaging biomarkers
  • imaging response criteria
  • MacDonald criteria
  • perfusion MRI
  • RANO criteria
  • spectroscopy

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