Abstract
Images of the enzymes glucoamylase 1 and glucoamylase 2 and G1C (a proteolytically derived C-terminal fragment of glucoamylase 1) have been obtained by scanning tunnelling microscopy (STM). The images of glucoamylase 2 and G1C show that these proteins are nearly spherical globular proteins. In contrast, images of glucoamylase 1 show that it is a dumb-bell shaped globular protein. Problems encountered in (i) imaging these proteins and (ii) validating and interpreting the images obtained by STM are discussed.
Original language | English |
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Pages (from-to) | 1939-1942 |
Number of pages | 4 |
Journal | Analyst |
Volume | 119 |
Issue number | 9 |
DOIs | |
Publication status | Published - 1 Dec 1994 |
Externally published | Yes |