IL-17 cuts to the chase in colon cancer

Matthias Ernst; Tracy L Putoczki

doi:10.1016/j.immuni.2014.12.004

IL-17 cuts to the chase in colon cancer

Matthias Ernst, Tracy L Putoczki

Research output: Contribution to journal › Short Survey › Other › peer-review

17 Citations (Scopus)

Abstract

Although interleukin-17A (IL-17A) facilitates colon cancer development, its target cells remain elusive. In this issue of Immunity, Wang etal. (2014) now demonstrate that IL-17A receptors on the intestinal epithelium promote progression of APC mutant adenomas associated with IL-6 expression and that IL-17A confers chemotherapy resistance.

Original language	English
Pages (from-to)	880-882
Number of pages	3
Journal	Immunity
Volume	41
Issue number	6
DOIs	https://doi.org/10.1016/j.immuni.2014.12.004
Publication status	Published - 18 Dec 2014
Externally published	Yes

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10.1016/j.immuni.2014.12.004

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@article{f881dea47833401eaf674f481ccb1f29,

title = "IL-17 cuts to the chase in colon cancer",

abstract = "Although interleukin-17A (IL-17A) facilitates colon cancer development, its target cells remain elusive. In this issue of Immunity, Wang etal. (2014) now demonstrate that IL-17A receptors on the intestinal epithelium promote progression of APC mutant adenomas associated with IL-6 expression and that IL-17A confers chemotherapy resistance.",

author = "Matthias Ernst and Putoczki, {Tracy L}",

year = "2014",

month = dec,

day = "18",

doi = "10.1016/j.immuni.2014.12.004",

language = "English",

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journal = "Immunity",

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TY - JOUR

T1 - IL-17 cuts to the chase in colon cancer

AU - Ernst, Matthias

AU - Putoczki, Tracy L

PY - 2014/12/18

Y1 - 2014/12/18

N2 - Although interleukin-17A (IL-17A) facilitates colon cancer development, its target cells remain elusive. In this issue of Immunity, Wang etal. (2014) now demonstrate that IL-17A receptors on the intestinal epithelium promote progression of APC mutant adenomas associated with IL-6 expression and that IL-17A confers chemotherapy resistance.

AB - Although interleukin-17A (IL-17A) facilitates colon cancer development, its target cells remain elusive. In this issue of Immunity, Wang etal. (2014) now demonstrate that IL-17A receptors on the intestinal epithelium promote progression of APC mutant adenomas associated with IL-6 expression and that IL-17A confers chemotherapy resistance.

UR - http://www.scopus.com/inward/record.url?scp=84918497719&partnerID=8YFLogxK

U2 - 10.1016/j.immuni.2014.12.004

DO - 10.1016/j.immuni.2014.12.004

M3 - Short Survey

AN - SCOPUS:84918497719

SN - 1074-7613

VL - 41

SP - 880

EP - 882

JO - Immunity

JF - Immunity

IS - 6

ER -

IL-17 cuts to the chase in colon cancer

Abstract

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