IL-17 cuts to the chase in colon cancer

Matthias Ernst, Tracy L Putoczki

Research output: Contribution to journalShort SurveyOtherpeer-review

9 Citations (Scopus)

Abstract

Although interleukin-17A (IL-17A) facilitates colon cancer development, its target cells remain elusive. In this issue of Immunity, Wang etal. (2014) now demonstrate that IL-17A receptors on the intestinal epithelium promote progression of APC mutant adenomas associated with IL-6 expression and that IL-17A confers chemotherapy resistance.

Original languageEnglish
Pages (from-to)880-882
Number of pages3
JournalImmunity
Volume41
Issue number6
DOIs
Publication statusPublished - 18 Dec 2014
Externally publishedYes

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