IL-10 induces mesangial cell proliferation via a PDGF-dependent mechanism

T E Robertson, David J Nikolic-Paterson, Lynette A Hurst, Robert Charles Atkins, Stephen J Chadban

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7 Citations (Scopus)


Interleukin-10 (IL-10) is a mesangial cell growth factor in vivo and in vitro. However, the mechanism by which IL-10 exerts its mitogenic activity is not known. The aim of this study was to determine whether IL-10 induces mesangial cell proliferation in a PDGF-dependent or independent fashion.
Original languageEnglish
Pages (from-to)241 - 244
Number of pages4
JournalClinical & Experimental Immunology
Issue number2
Publication statusPublished - 2002

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