If You Like It Then You Shoulda Put Two “RINGs” on It: Delineating the Roles of vPRC1 and cPRC1

Evan Healy; Adrian P. Bracken

doi:10.1016/j.molcel.2020.02.002

If You Like It Then You Shoulda Put Two “RINGs” on It: Delineating the Roles of vPRC1 and cPRC1

Evan Healy, Adrian P. Bracken

Research output: Contribution to journal › Article › Other › peer-review

2 Citations (Scopus)

Abstract

To delineate the roles of variant (vPRC1) and canonical (cPRC1) Polycomb repressive complex 1, Blackledge et al. (2020) and Tamburri et al. (2020) elegantly disrupt RING1A/B catalytic activity without affecting stability of either complex and then explore the precise contribution of vPRC1-mediated H2AK119ub1 to Polycomb-mediated gene repression.

Original language	English
Pages (from-to)	685-687
Number of pages	3
Journal	Molecular Cell
Volume	77
Issue number	4
DOIs	https://doi.org/10.1016/j.molcel.2020.02.002
Publication status	Published - 20 Feb 2020
Externally published	Yes

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title = "If You Like It Then You Shoulda Put Two “RINGs” on It: Delineating the Roles of vPRC1 and cPRC1",

abstract = "To delineate the roles of variant (vPRC1) and canonical (cPRC1) Polycomb repressive complex 1, Blackledge et al. (2020) and Tamburri et al. (2020) elegantly disrupt RING1A/B catalytic activity without affecting stability of either complex and then explore the precise contribution of vPRC1-mediated H2AK119ub1 to Polycomb-mediated gene repression.",

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If You Like It Then You Shoulda Put Two “RINGs” on It: Delineating the Roles of vPRC1 and cPRC1

Abstract

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