If You Like It Then You Shoulda Put Two “RINGs” on It: Delineating the Roles of vPRC1 and cPRC1

Evan Healy; Adrian P. Bracken

doi:10.1016/j.molcel.2020.02.002

If You Like It Then You Shoulda Put Two “RINGs” on It: Delineating the Roles of vPRC1 and cPRC1

Evan Healy, Adrian P. Bracken

Research output: Contribution to journal › Article › Other › peer-review

2 Citations (Scopus)

Abstract

To delineate the roles of variant (vPRC1) and canonical (cPRC1) Polycomb repressive complex 1, Blackledge et al. (2020) and Tamburri et al. (2020) elegantly disrupt RING1A/B catalytic activity without affecting stability of either complex and then explore the precise contribution of vPRC1-mediated H2AK119ub1 to Polycomb-mediated gene repression.

Original language	English
Pages (from-to)	685-687
Number of pages	3
Journal	Molecular Cell
Volume	77
Issue number	4
DOIs	https://doi.org/10.1016/j.molcel.2020.02.002
Publication status	Published - 20 Feb 2020
Externally published	Yes

Access to Document

10.1016/j.molcel.2020.02.002

Cite this

@article{471b978390664ff0b591101feb7247ee,

title = "If You Like It Then You Shoulda Put Two “RINGs” on It: Delineating the Roles of vPRC1 and cPRC1",

abstract = "To delineate the roles of variant (vPRC1) and canonical (cPRC1) Polycomb repressive complex 1, Blackledge et al. (2020) and Tamburri et al. (2020) elegantly disrupt RING1A/B catalytic activity without affecting stability of either complex and then explore the precise contribution of vPRC1-mediated H2AK119ub1 to Polycomb-mediated gene repression.",

author = "Evan Healy and Bracken, {Adrian P.}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = feb,

day = "20",

doi = "10.1016/j.molcel.2020.02.002",

language = "English",

volume = "77",

pages = "685--687",

journal = "Molecular Cell",

issn = "1097-2765",

publisher = "Elsevier",

number = "4",

}

TY - JOUR

T1 - If You Like It Then You Shoulda Put Two “RINGs” on It

T2 - Delineating the Roles of vPRC1 and cPRC1

AU - Healy, Evan

AU - Bracken, Adrian P.

PY - 2020/2/20

Y1 - 2020/2/20

N2 - To delineate the roles of variant (vPRC1) and canonical (cPRC1) Polycomb repressive complex 1, Blackledge et al. (2020) and Tamburri et al. (2020) elegantly disrupt RING1A/B catalytic activity without affecting stability of either complex and then explore the precise contribution of vPRC1-mediated H2AK119ub1 to Polycomb-mediated gene repression.

AB - To delineate the roles of variant (vPRC1) and canonical (cPRC1) Polycomb repressive complex 1, Blackledge et al. (2020) and Tamburri et al. (2020) elegantly disrupt RING1A/B catalytic activity without affecting stability of either complex and then explore the precise contribution of vPRC1-mediated H2AK119ub1 to Polycomb-mediated gene repression.

UR - http://www.scopus.com/inward/record.url?scp=85079377351&partnerID=8YFLogxK

U2 - 10.1016/j.molcel.2020.02.002

DO - 10.1016/j.molcel.2020.02.002

M3 - Article

C2 - 32084351

AN - SCOPUS:85079377351

SN - 1097-2765

VL - 77

SP - 685

EP - 687

JO - Molecular Cell

JF - Molecular Cell

IS - 4

ER -

If You Like It Then You Shoulda Put Two “RINGs” on It: Delineating the Roles of vPRC1 and cPRC1

Abstract

Access to Document

Other files and links

Cite this