In this report we have employed an alternative tissue‐sectioning procedure which provides a plan view of intra‐epithelial cell populations within the airway wall. Immunoperoxidase staining of such sections for class II MHC (Ia) antigen revealed the presence of a highly developed intra‐epithelial network of Ia‐positive dendritic cells, which was not evident employing conventional cross‐ or longitudinal tissue sections. This finding has important implications for the study of mechanisms underlying allergic and infectious diseases of the respiratory tract.
|Number of pages||5|
|Journal||Clinical and Experimental Allergy|
|Publication status||Published - 1 Jan 1989|