Hypoglycemia and risk of death in critically ill patients

Simon R Finfer, Bette Liu, Dean R Chittock, Robyn Norton, John A Myburgh, Colin McArthur, Imogen Mitchell, Denise Foster, Vinay Dhingra, William R Henderson, Juan J Ronco, Rinaldo Bellomo, Deborah J Cook, Ellen McDonald, Peter Dodek, Paul Hebert, Daren K Heyland, Bruce Robinson

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Whether hypoglycemia leads to death in critically ill patients is unclear. METHODS: We examined the associations between moderate and severe hypoglycemia (blood glucose, 41 to 70 mg per deciliter [2.3 to 3.9 mmol per liter] and =40 mg per deciliter [2.2 mmol per liter], respectively) and death among 6026 critically ill patients in intensive care units (ICUs). Patients were randomly assigned to intensive or conventional glucose control. We used Cox regression analysis with adjustment for treatment assignment and for baseline and postrandomization covariates.
Original languageEnglish
Pages (from-to)1108 - 1118
Number of pages11
JournalNew England Journal of Medicine
Volume367
Issue number12
DOIs
Publication statusPublished - 2012
Externally publishedYes

Cite this

Finfer, S. R., Liu, B., Chittock, D. R., Norton, R., Myburgh, J. A., McArthur, C., ... Robinson, B. (2012). Hypoglycemia and risk of death in critically ill patients. New England Journal of Medicine, 367(12), 1108 - 1118. https://doi.org/10.1056/NEJMoa1204942
Finfer, Simon R ; Liu, Bette ; Chittock, Dean R ; Norton, Robyn ; Myburgh, John A ; McArthur, Colin ; Mitchell, Imogen ; Foster, Denise ; Dhingra, Vinay ; Henderson, William R ; Ronco, Juan J ; Bellomo, Rinaldo ; Cook, Deborah J ; McDonald, Ellen ; Dodek, Peter ; Hebert, Paul ; Heyland, Daren K ; Robinson, Bruce. / Hypoglycemia and risk of death in critically ill patients. In: New England Journal of Medicine. 2012 ; Vol. 367, No. 12. pp. 1108 - 1118.
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author = "Finfer, {Simon R} and Bette Liu and Chittock, {Dean R} and Robyn Norton and Myburgh, {John A} and Colin McArthur and Imogen Mitchell and Denise Foster and Vinay Dhingra and Henderson, {William R} and Ronco, {Juan J} and Rinaldo Bellomo and Cook, {Deborah J} and Ellen McDonald and Peter Dodek and Paul Hebert and Heyland, {Daren K} and Bruce Robinson",
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Finfer, SR, Liu, B, Chittock, DR, Norton, R, Myburgh, JA, McArthur, C, Mitchell, I, Foster, D, Dhingra, V, Henderson, WR, Ronco, JJ, Bellomo, R, Cook, DJ, McDonald, E, Dodek, P, Hebert, P, Heyland, DK & Robinson, B 2012, 'Hypoglycemia and risk of death in critically ill patients' New England Journal of Medicine, vol. 367, no. 12, pp. 1108 - 1118. https://doi.org/10.1056/NEJMoa1204942

Hypoglycemia and risk of death in critically ill patients. / Finfer, Simon R; Liu, Bette; Chittock, Dean R; Norton, Robyn; Myburgh, John A; McArthur, Colin; Mitchell, Imogen; Foster, Denise; Dhingra, Vinay; Henderson, William R; Ronco, Juan J; Bellomo, Rinaldo; Cook, Deborah J; McDonald, Ellen; Dodek, Peter; Hebert, Paul; Heyland, Daren K; Robinson, Bruce.

In: New England Journal of Medicine, Vol. 367, No. 12, 2012, p. 1108 - 1118.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Norton, Robyn

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AU - McArthur, Colin

AU - Mitchell, Imogen

AU - Foster, Denise

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AU - Ronco, Juan J

AU - Bellomo, Rinaldo

AU - Cook, Deborah J

AU - McDonald, Ellen

AU - Dodek, Peter

AU - Hebert, Paul

AU - Heyland, Daren K

AU - Robinson, Bruce

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