TY - JOUR
T1 - Hypertensive disorders in pregnancy – Trends over eight years
T2 - A population-based cohort study
AU - Wertaschnigg, Dagmar
AU - Selvaratnam, Roshan J.
AU - Rolnik, Daniel L.
AU - Davey, Mary-Ann
AU - Anil, Shirin
AU - Mol, Ben W.J.
AU - Reddy, Maya
AU - da Silva Costa, Fabricio
N1 - Funding Information:
We are grateful to CCOPMM for providing access to the data used for this project and for the assistance of the staff at the Consultative Councils Unit, Safer Care Victoria. The conclusions, findings, opinions and views or recommendations expressed in this paper are those of the authors and do not necessarily reflect those of CCOPMM.
Funding Information:
DW is supported by a grant from the Paracelsus Medical University Salzburg, Austria (PMU Research Fund – PMU FFF Number: L-18/02/006-WET) and by Drs Haackert Foundation, Germany.
Publisher Copyright:
© 2022 International Society for the Study of Hypertension in Pregnancy
PY - 2022/6
Y1 - 2022/6
N2 - Objective: To describe the incidence and trends of hypertensive disorders of pregnancy and adverse pregnancy outcomes in recent years in Victoria, Australia. Design: Retrospective population-based cohort study, 2010 to 2017. Setting: State of Victoria, Australia. Participants: Population-based cohort study. Main outcome measures: Incidence of hypertensive disorders and its subtypes over time. Composite of major adverse maternal and perinatal outcome. Results: The incidence of hypertensive disorders (n = 36,406/614,524 pregnancies with 624,193 births) and all its subtypes has been stable, (n = 4,192/73,235 = 5.7% in 2010 to 4,601/78,576 = 5.9% in 2017). Compared to no hypertension, hypertensive disorders were associated with medically-initiated birth (aOR 4.70 [4.56, 4.84]), caesarean section (aOR 1.46 [1.43, 1.50]), placental abruption (aOR 1.94 [1.69, 2.22]), maternal intensive care or high-dependency unit admission (aOR 6.80 [6.45, 7.17]), composite of major adverse maternal outcome (aOR 3.87 [3.70, 4.04]), and composite of major adverse perinatal outcome (aOR 1.63 [1.56, 1.70]). The worst maternal and perinatal outcomes were among women with superimposed and early preterm preeclampsia. Conclusion: The incidence of all hypertensive disorders in pregnancy has remained stable over time. Early-onset preeclampsia and superimposed preeclampsia were most strongly associated with adverse pregnancy outcomes.
AB - Objective: To describe the incidence and trends of hypertensive disorders of pregnancy and adverse pregnancy outcomes in recent years in Victoria, Australia. Design: Retrospective population-based cohort study, 2010 to 2017. Setting: State of Victoria, Australia. Participants: Population-based cohort study. Main outcome measures: Incidence of hypertensive disorders and its subtypes over time. Composite of major adverse maternal and perinatal outcome. Results: The incidence of hypertensive disorders (n = 36,406/614,524 pregnancies with 624,193 births) and all its subtypes has been stable, (n = 4,192/73,235 = 5.7% in 2010 to 4,601/78,576 = 5.9% in 2017). Compared to no hypertension, hypertensive disorders were associated with medically-initiated birth (aOR 4.70 [4.56, 4.84]), caesarean section (aOR 1.46 [1.43, 1.50]), placental abruption (aOR 1.94 [1.69, 2.22]), maternal intensive care or high-dependency unit admission (aOR 6.80 [6.45, 7.17]), composite of major adverse maternal outcome (aOR 3.87 [3.70, 4.04]), and composite of major adverse perinatal outcome (aOR 1.63 [1.56, 1.70]). The worst maternal and perinatal outcomes were among women with superimposed and early preterm preeclampsia. Conclusion: The incidence of all hypertensive disorders in pregnancy has remained stable over time. Early-onset preeclampsia and superimposed preeclampsia were most strongly associated with adverse pregnancy outcomes.
KW - Hypertension in pregnancy
KW - Maternal and perinatal morbidity
KW - Population cohort study
KW - Preeclampsia
KW - Pregnancy outcomes
UR - http://www.scopus.com/inward/record.url?scp=85125246583&partnerID=8YFLogxK
U2 - 10.1016/j.preghy.2022.02.006
DO - 10.1016/j.preghy.2022.02.006
M3 - Article
C2 - 35228109
AN - SCOPUS:85125246583
SN - 2210-7789
VL - 28
SP - 60
EP - 65
JO - Pregnancy Hypertension
JF - Pregnancy Hypertension
ER -