HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

Anne M Verhagen; John Silke; Paul G Ekert; Miha Pakusch; Hitto Kaufmann; Lisa M Connolly; Catherine L Day; Anjali Tikoo; Richard Edward Burke; Carolyn Wrobel; Robert L Moritz; Richard J Simpson; David L Vaux

doi:10.1074/jbc.M109891200

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

Anne M Verhagen, John Silke, Paul G Ekert, Miha Pakusch, Hitto Kaufmann, Lisa M Connolly, Catherine L Day, Anjali Tikoo, Richard Edward Burke, Carolyn Wrobel, Robert L Moritz, Richard J Simpson, David L Vaux

School of Biological Sciences

Research output: Contribution to journal › Article › Research › peer-review

462 Citations (Scopus)

Original language	English
Pages (from-to)	445 - 454
Number of pages	10
Journal	Journal of Biological Chemistry
Volume	277
Issue number	1
DOIs	https://doi.org/10.1074/jbc.M109891200
Publication status	Published - 2002

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10.1074/jbc.M109891200

Cite this

Verhagen, A. M., Silke, J., Ekert, P. G., Pakusch, M., Kaufmann, H., Connolly, L. M., Day, C. L., Tikoo, A., Burke, R. E., Wrobel, C., Moritz, R. L., Simpson, R. J., & Vaux, D. L. (2002). HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins. Journal of Biological Chemistry, 277(1), 445 - 454. https://doi.org/10.1074/jbc.M109891200

Verhagen, Anne M ; Silke, John ; Ekert, Paul G ; Pakusch, Miha ; Kaufmann, Hitto ; Connolly, Lisa M ; Day, Catherine L ; Tikoo, Anjali ; Burke, Richard Edward ; Wrobel, Carolyn ; Moritz, Robert L ; Simpson, Richard J ; Vaux, David L. / HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins. In: Journal of Biological Chemistry. 2002 ; Vol. 277, No. 1. pp. 445 - 454.

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author = "Verhagen, {Anne M} and John Silke and Ekert, {Paul G} and Miha Pakusch and Hitto Kaufmann and Connolly, {Lisa M} and Day, {Catherine L} and Anjali Tikoo and Burke, {Richard Edward} and Carolyn Wrobel and Moritz, {Robert L} and Simpson, {Richard J} and Vaux, {David L}",

year = "2002",

doi = "10.1074/jbc.M109891200",

language = "English",

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Verhagen, AM, Silke, J, Ekert, PG, Pakusch, M, Kaufmann, H, Connolly, LM, Day, CL, Tikoo, A, Burke, RE, Wrobel, C, Moritz, RL, Simpson, RJ & Vaux, DL 2002, 'HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins', Journal of Biological Chemistry, vol. 277, no. 1, pp. 445 - 454. https://doi.org/10.1074/jbc.M109891200

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins. / Verhagen, Anne M; Silke, John; Ekert, Paul G; Pakusch, Miha; Kaufmann, Hitto; Connolly, Lisa M; Day, Catherine L; Tikoo, Anjali; Burke, Richard Edward; Wrobel, Carolyn; Moritz, Robert L; Simpson, Richard J; Vaux, David L.

In: Journal of Biological Chemistry, Vol. 277, No. 1, 2002, p. 445 - 454.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

AU - Verhagen, Anne M

AU - Silke, John

AU - Ekert, Paul G

AU - Pakusch, Miha

AU - Kaufmann, Hitto

AU - Connolly, Lisa M

AU - Day, Catherine L

AU - Tikoo, Anjali

AU - Burke, Richard Edward

AU - Wrobel, Carolyn

AU - Moritz, Robert L

AU - Simpson, Richard J

AU - Vaux, David L

PY - 2002

Y1 - 2002

U2 - 10.1074/jbc.M109891200

DO - 10.1074/jbc.M109891200

M3 - Article

VL - 277

SP - 445

EP - 454

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 1083-351X

IS - 1

ER -