How to ventilate patients without ARDS?

F. D. Simonis; A. Braber; H. P. Gelissen; J. Heidt; J. Horn; G. Innemee; E. de Jonge; N. P. Juffermans; P. E. Spronk; P. R. Tuinman; M. Vriends; R. B. de Wilde; A. Serpa Neto; M. Gama de Abreu; P. Pelosi; M. J. Schultz

How to ventilate patients without ARDS?

F. D. Simonis, A. Braber, H. P. Gelissen, J. Heidt, J. Horn, G. Innemee, E. de Jonge, N. P. Juffermans, P. E. Spronk, P. R. Tuinman, M. Vriends, R. B. de Wilde, A. Serpa Neto, M. Gama de Abreu, P. Pelosi, M. J. Schultz

Research output: Contribution to journal › Review Article › Research › peer-review

Abstract

Certain mechanical ventilation strategies could prevent the injury caused by this intervention. One element of so-called ‘lung–protective’ ventilation is the use of low tidal volumes. It is uncertain whether high levels of positive end-expiratory pressures have lung-protective properties as well. There are indications that high oxygen fractions of inspired air, or high blood oxygen targets, are harmful. This review summarises recently obtained clinical evidence for protective roles of low tidal volumes, high levels of PEEP, and low fractions of inspired oxygen in surgery patients, and critically ill patients without ARDS.

Original language	English
Pages (from-to)	14-18
Number of pages	5
Journal	Netherlands Journal of Critical Care
Volume	21
Issue number	3
Publication status	Published - Jun 2015
Externally published	Yes

Keywords

Critical care
Intensive care unit
Intra–operative ventilation
Mechanical ventilation
Non injured lungs
Oxygen fraction
Positive end–expiratory pressure
Protective ventilation
Tidal volume
Ventilation–associated lung injury

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Cite this

@article{1b4e81789dc64961a6570e632150af88,

title = "How to ventilate patients without ARDS?",

abstract = "Certain mechanical ventilation strategies could prevent the injury caused by this intervention. One element of so-called {\textquoteleft}lung–protective{\textquoteright} ventilation is the use of low tidal volumes. It is uncertain whether high levels of positive end-expiratory pressures have lung-protective properties as well. There are indications that high oxygen fractions of inspired air, or high blood oxygen targets, are harmful. This review summarises recently obtained clinical evidence for protective roles of low tidal volumes, high levels of PEEP, and low fractions of inspired oxygen in surgery patients, and critically ill patients without ARDS.",

keywords = "Critical care, Intensive care unit, Intra–operative ventilation, Mechanical ventilation, Non injured lungs, Oxygen fraction, Positive end–expiratory pressure, Protective ventilation, Tidal volume, Ventilation–associated lung injury",

author = "Simonis, {F. D.} and A. Braber and Gelissen, {H. P.} and J. Heidt and J. Horn and G. Innemee and {de Jonge}, E. and Juffermans, {N. P.} and Spronk, {P. E.} and Tuinman, {P. R.} and M. Vriends and {de Wilde}, {R. B.} and {Serpa Neto}, A. and {de Abreu}, {M. Gama} and P. Pelosi and Schultz, {M. J.}",

year = "2015",

month = jun,

language = "English",

volume = "21",

pages = "14--18",

journal = "Netherlands Journal of Critical Care",

issn = "1569-3511",