How to read a report of a randomized controlled trial

Min Jun, Sophia Zoungas, Vlado Perkovic, Angela Webster

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Abstract

Proper evaluation of up-to-date clinical evidence is essential for the provision of optimal patient care. Randomized controlled trials (RCTs) are the ideal study type to investigate the benefit or harm of an intervention, such as a drug therapy. RCTs aims to avoid biased assessment of clinical interventions through the even distribution of both known and unknown factors that may influence outcomes. However, not all RCTs are well designed, conducted or reported. As such, the clinician needs to critically appraise RCTs in order to determine their strengths and weaknesses. This paper aims to explain how to approach critical appraisal, by highlighting and illustrating important questions that help determine the reliability of results from randomized trials.
Original languageEnglish
Pages (from-to)153 - 157
Number of pages5
JournalNephrology
Volume15
Issue number2
DOIs
Publication statusPublished - 2010

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