How to diagnose multiple sclerosis and what are the pitfalls

C. Shaw, C. Chapman, H. Butzkueven

Research output: Contribution to journalReview ArticleResearchpeer-review

5 Citations (Scopus)


The task of confirming a diagnosis of multiple sclerosis (MS), one of the commonest neurological disorders affecting young adults, has altered significantly in the magnetic resonance imaging era. Conversely, key principles, most notably objective documentation of neurological dissemination in time and space, remain fundamental to the process. Clinical acumen and experience are equally as crucial as an ability to interpret relevant investigations. Recognising typical clinical patterns, addressing potential 'mimics', and stratifying prognosis of a clinically isolated syndrome are just some of the challenges inherent in diagnosing MS.

Original languageEnglish
Pages (from-to)792-799
Number of pages8
JournalInternal Medicine Journal
Issue number12
Publication statusPublished - 1 Dec 2009


  • Clinically isolated syndrome
  • Differential diagnosis
  • Magnetic resonance imaging
  • Multiple sclerosis
  • Pitfalls
  • Practical guide

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