The ability of a T cell receptor (TCR) to directly recognize foreign (allogeneic)-major histocompatibility complex (MHC) molecules underlies T cell-mediated rejection in patients receiving allogeneic organ transplants. In this issue, Colf et al. (2007) reveal that instead of mimicking the interactions formed with a self MHC, a single TCR adopts a completely different strategy to recognize a foreign MHC.
|Pages (from-to)||19 - 20|
|Number of pages||2|
|Publication status||Published - 2007|