Over 1000 sequences likely to encode G protein-coupled receptors (GPCRs) are currently available in publicly accessible and proprietary databases and this number may grow with the refinement of a number of different genomes. However, despite recent efforts in the crystallization of these proteins, homology modeling approaches are becoming widely used as a method for obtaining quantitative and qualitative information for structure-based drug design as well as the interpretation of experimental data.
|Title of host publication||Methods in Molecular Biology - G Protein-Coupled Receptors in Drug Delivery|
|Editors||Wayne R Leifert|
|Place of Publication||USA|
|Pages||97 - 113|
|Number of pages||17|
|Publication status||Published - 2009|