HLA Patterns in Australian Patients with Insulin Dependent Diabetes Mellitus (IDDM)

P. Zimmet; P. Kiely; R. Cross; J. Court; J. Bornstein

doi:10.1111/j.1445-5994.1979.tb04191.x

HLA Patterns in Australian Patients with Insulin Dependent Diabetes Mellitus (IDDM)

P. Zimmet, P. Kiely, R. Cross, J. Court, J. Bornstein

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Summary: HLA antigens were determined in 169 Australian patients with insulin dependent diabetes mellitus (IDDM). HLA‐B8 (47·9% v. 23·8%) and B15 (18·9% v. 8·2%) were significantly more frequent in the IDDM patients than in 1460 controls. The relative risks for developing IDDM in people carrying these antigens were 2·94 and 2·59 respectively. Carriers of the B8/B15 genotype had a relative risk of 5·48. These HLA associations in Australian IDDM patients are similar to those reported in other predominantly Caucasian populations.

Original language	English
Pages (from-to)	633-636
Number of pages	4
Journal	Australian and New Zealand Journal of Medicine
Volume	9
Issue number	6
DOIs	https://doi.org/10.1111/j.1445-5994.1979.tb04191.x
Publication status	Published - Dec 1979
Externally published	Yes

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10.1111/j.1445-5994.1979.tb04191.x

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title = "HLA Patterns in Australian Patients with Insulin Dependent Diabetes Mellitus (IDDM)",

abstract = "Summary: HLA antigens were determined in 169 Australian patients with insulin dependent diabetes mellitus (IDDM). HLA‐B8 (47·9% v. 23·8%) and B15 (18·9% v. 8·2%) were significantly more frequent in the IDDM patients than in 1460 controls. The relative risks for developing IDDM in people carrying these antigens were 2·94 and 2·59 respectively. Carriers of the B8/B15 genotype had a relative risk of 5·48. These HLA associations in Australian IDDM patients are similar to those reported in other predominantly Caucasian populations.",

author = "P. Zimmet and P. Kiely and R. Cross and J. Court and J. Bornstein",

year = "1979",

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doi = "10.1111/j.1445-5994.1979.tb04191.x",

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AU - Zimmet, P.

AU - Kiely, P.

AU - Cross, R.

AU - Court, J.

AU - Bornstein, J.

PY - 1979/12

Y1 - 1979/12

N2 - Summary: HLA antigens were determined in 169 Australian patients with insulin dependent diabetes mellitus (IDDM). HLA‐B8 (47·9% v. 23·8%) and B15 (18·9% v. 8·2%) were significantly more frequent in the IDDM patients than in 1460 controls. The relative risks for developing IDDM in people carrying these antigens were 2·94 and 2·59 respectively. Carriers of the B8/B15 genotype had a relative risk of 5·48. These HLA associations in Australian IDDM patients are similar to those reported in other predominantly Caucasian populations.

AB - Summary: HLA antigens were determined in 169 Australian patients with insulin dependent diabetes mellitus (IDDM). HLA‐B8 (47·9% v. 23·8%) and B15 (18·9% v. 8·2%) were significantly more frequent in the IDDM patients than in 1460 controls. The relative risks for developing IDDM in people carrying these antigens were 2·94 and 2·59 respectively. Carriers of the B8/B15 genotype had a relative risk of 5·48. These HLA associations in Australian IDDM patients are similar to those reported in other predominantly Caucasian populations.

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DO - 10.1111/j.1445-5994.1979.tb04191.x

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JO - Internal Medicine Journal

JF - Internal Medicine Journal

SN - 1444-0903

IS - 6

ER -

HLA Patterns in Australian Patients with Insulin Dependent Diabetes Mellitus (IDDM)

Abstract

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