Historical epidemiology of hepatitis C virus (HCV) in selected countries

Philip Bruggmann, T Berg, Anne Lindebo Holm Ovrehus, Christophe A Moreno, Carlos Eduardo Brandao-Mello, Francoise Roudot-Thoraval, R T Marinho, M Sherman, Stephen D Ryder, J Sperl, Ulus Salih Akarca, Ismail Balik, Florian K Bihl, M Bilodeau, A J Blasco, Maria Asuncion Buti, Filipe Calinas, J L Calleja, Hugo Cheinquer, P B Christensen & 73 others M Clausen, H S M Coelho, Markus Cornberg, Matthew E Cramp, Gregory J Dore, Wahid H Doss, Ann Sofi Duberg, Mohammed H El-Sayed, Gul Ergor, Gamal Esmat, Chris Estes, K Falconer, J Felix, M L G Ferraz, P R Ferreira, Sona Frankova, Javier Garcia-Samaniego, J Gerstoft, Jose A Giria, Fernando Lopes Goncales, Erin E Gower, Michael Gschwantler, M Guimaraes Pessoa, Christophe Hezode, H Hofer, P Husa, Ramazan Idilman, M Kaberg, Kelly Kaita, Achim Kautz, Sabahattin Kaymakoglu, Mel Krajden, H Krarup, Wim J Laleman, D Lavanchy, P Lazaro, P Marotta, Stefan Mauss, Maria Cassia Jacintho Mendes-Correa, B Mullhaupt, Robert P Myers, Francesco Negro, V Nemecek, Necati Ormeci, J Parkes, Kevork Minas Peltekian, Alnoor S Ramji, Homie A Razavi, N Reis, Stuart Keith Roberts, William M C Rosenberg, Rui Sarmento-Castro, Christoph M Sarrazin, David Semela, Gamal Elsayed Shiha, William Sievert, Peter Starkel, R E Stauber, Alexander James V Thompson, P Urbanek, I Van Thiel, H Van Vlierberghe, Dominique M Vandijck, W Vogel, Imam A Waked, Heiner Wedemeyer, N Weis, Johannes Wiegand, Ayman Yosry, Amany Zekry, P Van Damme, Soo Aleman, S J Hindman

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171 Citations (Scopus)

Abstract

Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3 in Austria, England and Germany to 8.5 in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.
Original languageEnglish
Pages (from-to)5 - 33
Number of pages29
JournalJournal of Viral Hepatitis
Volume21
Issue numberSupplement S1
DOIs
Publication statusPublished - 2014

Cite this

Bruggmann, P., Berg, T., Ovrehus, A. L. H., Moreno, C. A., Brandao-Mello, C. E., Roudot-Thoraval, F., ... Hindman, S. J. (2014). Historical epidemiology of hepatitis C virus (HCV) in selected countries. Journal of Viral Hepatitis, 21(Supplement S1), 5 - 33. https://doi.org/10.1111/jvh.12247
Bruggmann, Philip ; Berg, T ; Ovrehus, Anne Lindebo Holm ; Moreno, Christophe A ; Brandao-Mello, Carlos Eduardo ; Roudot-Thoraval, Francoise ; Marinho, R T ; Sherman, M ; Ryder, Stephen D ; Sperl, J ; Akarca, Ulus Salih ; Balik, Ismail ; Bihl, Florian K ; Bilodeau, M ; Blasco, A J ; Buti, Maria Asuncion ; Calinas, Filipe ; Calleja, J L ; Cheinquer, Hugo ; Christensen, P B ; Clausen, M ; Coelho, H S M ; Cornberg, Markus ; Cramp, Matthew E ; Dore, Gregory J ; Doss, Wahid H ; Duberg, Ann Sofi ; El-Sayed, Mohammed H ; Ergor, Gul ; Esmat, Gamal ; Estes, Chris ; Falconer, K ; Felix, J ; Ferraz, M L G ; Ferreira, P R ; Frankova, Sona ; Garcia-Samaniego, Javier ; Gerstoft, J ; Giria, Jose A ; Goncales, Fernando Lopes ; Gower, Erin E ; Gschwantler, Michael ; Guimaraes Pessoa, M ; Hezode, Christophe ; Hofer, H ; Husa, P ; Idilman, Ramazan ; Kaberg, M ; Kaita, Kelly ; Kautz, Achim ; Kaymakoglu, Sabahattin ; Krajden, Mel ; Krarup, H ; Laleman, Wim J ; Lavanchy, D ; Lazaro, P ; Marotta, P ; Mauss, Stefan ; Mendes-Correa, Maria Cassia Jacintho ; Mullhaupt, B ; Myers, Robert P ; Negro, Francesco ; Nemecek, V ; Ormeci, Necati ; Parkes, J ; Peltekian, Kevork Minas ; Ramji, Alnoor S ; Razavi, Homie A ; Reis, N ; Roberts, Stuart Keith ; Rosenberg, William M C ; Sarmento-Castro, Rui ; Sarrazin, Christoph M ; Semela, David ; Shiha, Gamal Elsayed ; Sievert, William ; Starkel, Peter ; Stauber, R E ; Thompson, Alexander James V ; Urbanek, P ; Van Thiel, I ; Van Vlierberghe, H ; Vandijck, Dominique M ; Vogel, W ; Waked, Imam A ; Wedemeyer, Heiner ; Weis, N ; Wiegand, Johannes ; Yosry, Ayman ; Zekry, Amany ; Van Damme, P ; Aleman, Soo ; Hindman, S J. / Historical epidemiology of hepatitis C virus (HCV) in selected countries. In: Journal of Viral Hepatitis. 2014 ; Vol. 21, No. Supplement S1. pp. 5 - 33.
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title = "Historical epidemiology of hepatitis C virus (HCV) in selected countries",
abstract = "Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3 in Austria, England and Germany to 8.5 in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.",
author = "Philip Bruggmann and T Berg and Ovrehus, {Anne Lindebo Holm} and Moreno, {Christophe A} and Brandao-Mello, {Carlos Eduardo} and Francoise Roudot-Thoraval and Marinho, {R T} and M Sherman and Ryder, {Stephen D} and J Sperl and Akarca, {Ulus Salih} and Ismail Balik and Bihl, {Florian K} and M Bilodeau and Blasco, {A J} and Buti, {Maria Asuncion} and Filipe Calinas and Calleja, {J L} and Hugo Cheinquer and Christensen, {P B} and M Clausen and Coelho, {H S M} and Markus Cornberg and Cramp, {Matthew E} and Dore, {Gregory J} and Doss, {Wahid H} and Duberg, {Ann Sofi} and El-Sayed, {Mohammed H} and Gul Ergor and Gamal Esmat and Chris Estes and K Falconer and J Felix and Ferraz, {M L G} and Ferreira, {P R} and Sona Frankova and Javier Garcia-Samaniego and J Gerstoft and Giria, {Jose A} and Goncales, {Fernando Lopes} and Gower, {Erin E} and Michael Gschwantler and {Guimaraes Pessoa}, M and Christophe Hezode and H Hofer and P Husa and Ramazan Idilman and M Kaberg and Kelly Kaita and Achim Kautz and Sabahattin Kaymakoglu and Mel Krajden and H Krarup and Laleman, {Wim J} and D Lavanchy and P Lazaro and P Marotta and Stefan Mauss and Mendes-Correa, {Maria Cassia Jacintho} and B Mullhaupt and Myers, {Robert P} and Francesco Negro and V Nemecek and Necati Ormeci and J Parkes and Peltekian, {Kevork Minas} and Ramji, {Alnoor S} and Razavi, {Homie A} and N Reis and Roberts, {Stuart Keith} and Rosenberg, {William M C} and Rui Sarmento-Castro and Sarrazin, {Christoph M} and David Semela and Shiha, {Gamal Elsayed} and William Sievert and Peter Starkel and Stauber, {R E} and Thompson, {Alexander James V} and P Urbanek and {Van Thiel}, I and {Van Vlierberghe}, H and Vandijck, {Dominique M} and W Vogel and Waked, {Imam A} and Heiner Wedemeyer and N Weis and Johannes Wiegand and Ayman Yosry and Amany Zekry and {Van Damme}, P and Soo Aleman and Hindman, {S J}",
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Bruggmann, P, Berg, T, Ovrehus, ALH, Moreno, CA, Brandao-Mello, CE, Roudot-Thoraval, F, Marinho, RT, Sherman, M, Ryder, SD, Sperl, J, Akarca, US, Balik, I, Bihl, FK, Bilodeau, M, Blasco, AJ, Buti, MA, Calinas, F, Calleja, JL, Cheinquer, H, Christensen, PB, Clausen, M, Coelho, HSM, Cornberg, M, Cramp, ME, Dore, GJ, Doss, WH, Duberg, AS, El-Sayed, MH, Ergor, G, Esmat, G, Estes, C, Falconer, K, Felix, J, Ferraz, MLG, Ferreira, PR, Frankova, S, Garcia-Samaniego, J, Gerstoft, J, Giria, JA, Goncales, FL, Gower, EE, Gschwantler, M, Guimaraes Pessoa, M, Hezode, C, Hofer, H, Husa, P, Idilman, R, Kaberg, M, Kaita, K, Kautz, A, Kaymakoglu, S, Krajden, M, Krarup, H, Laleman, WJ, Lavanchy, D, Lazaro, P, Marotta, P, Mauss, S, Mendes-Correa, MCJ, Mullhaupt, B, Myers, RP, Negro, F, Nemecek, V, Ormeci, N, Parkes, J, Peltekian, KM, Ramji, AS, Razavi, HA, Reis, N, Roberts, SK, Rosenberg, WMC, Sarmento-Castro, R, Sarrazin, CM, Semela, D, Shiha, GE, Sievert, W, Starkel, P, Stauber, RE, Thompson, AJV, Urbanek, P, Van Thiel, I, Van Vlierberghe, H, Vandijck, DM, Vogel, W, Waked, IA, Wedemeyer, H, Weis, N, Wiegand, J, Yosry, A, Zekry, A, Van Damme, P, Aleman, S & Hindman, SJ 2014, 'Historical epidemiology of hepatitis C virus (HCV) in selected countries', Journal of Viral Hepatitis, vol. 21, no. Supplement S1, pp. 5 - 33. https://doi.org/10.1111/jvh.12247

Historical epidemiology of hepatitis C virus (HCV) in selected countries. / Bruggmann, Philip; Berg, T; Ovrehus, Anne Lindebo Holm; Moreno, Christophe A; Brandao-Mello, Carlos Eduardo; Roudot-Thoraval, Francoise; Marinho, R T; Sherman, M; Ryder, Stephen D; Sperl, J; Akarca, Ulus Salih; Balik, Ismail; Bihl, Florian K; Bilodeau, M; Blasco, A J; Buti, Maria Asuncion; Calinas, Filipe; Calleja, J L; Cheinquer, Hugo; Christensen, P B; Clausen, M; Coelho, H S M; Cornberg, Markus; Cramp, Matthew E; Dore, Gregory J; Doss, Wahid H; Duberg, Ann Sofi; El-Sayed, Mohammed H; Ergor, Gul; Esmat, Gamal; Estes, Chris; Falconer, K; Felix, J; Ferraz, M L G; Ferreira, P R; Frankova, Sona; Garcia-Samaniego, Javier; Gerstoft, J; Giria, Jose A; Goncales, Fernando Lopes; Gower, Erin E; Gschwantler, Michael; Guimaraes Pessoa, M; Hezode, Christophe; Hofer, H; Husa, P; Idilman, Ramazan; Kaberg, M; Kaita, Kelly; Kautz, Achim; Kaymakoglu, Sabahattin; Krajden, Mel; Krarup, H; Laleman, Wim J; Lavanchy, D; Lazaro, P; Marotta, P; Mauss, Stefan; Mendes-Correa, Maria Cassia Jacintho; Mullhaupt, B; Myers, Robert P; Negro, Francesco; Nemecek, V; Ormeci, Necati; Parkes, J; Peltekian, Kevork Minas; Ramji, Alnoor S; Razavi, Homie A; Reis, N; Roberts, Stuart Keith; Rosenberg, William M C; Sarmento-Castro, Rui; Sarrazin, Christoph M; Semela, David; Shiha, Gamal Elsayed; Sievert, William; Starkel, Peter; Stauber, R E; Thompson, Alexander James V; Urbanek, P; Van Thiel, I; Van Vlierberghe, H; Vandijck, Dominique M; Vogel, W; Waked, Imam A; Wedemeyer, Heiner; Weis, N; Wiegand, Johannes; Yosry, Ayman; Zekry, Amany; Van Damme, P; Aleman, Soo; Hindman, S J.

In: Journal of Viral Hepatitis, Vol. 21, No. Supplement S1, 2014, p. 5 - 33.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Historical epidemiology of hepatitis C virus (HCV) in selected countries

AU - Bruggmann, Philip

AU - Berg, T

AU - Ovrehus, Anne Lindebo Holm

AU - Moreno, Christophe A

AU - Brandao-Mello, Carlos Eduardo

AU - Roudot-Thoraval, Francoise

AU - Marinho, R T

AU - Sherman, M

AU - Ryder, Stephen D

AU - Sperl, J

AU - Akarca, Ulus Salih

AU - Balik, Ismail

AU - Bihl, Florian K

AU - Bilodeau, M

AU - Blasco, A J

AU - Buti, Maria Asuncion

AU - Calinas, Filipe

AU - Calleja, J L

AU - Cheinquer, Hugo

AU - Christensen, P B

AU - Clausen, M

AU - Coelho, H S M

AU - Cornberg, Markus

AU - Cramp, Matthew E

AU - Dore, Gregory J

AU - Doss, Wahid H

AU - Duberg, Ann Sofi

AU - El-Sayed, Mohammed H

AU - Ergor, Gul

AU - Esmat, Gamal

AU - Estes, Chris

AU - Falconer, K

AU - Felix, J

AU - Ferraz, M L G

AU - Ferreira, P R

AU - Frankova, Sona

AU - Garcia-Samaniego, Javier

AU - Gerstoft, J

AU - Giria, Jose A

AU - Goncales, Fernando Lopes

AU - Gower, Erin E

AU - Gschwantler, Michael

AU - Guimaraes Pessoa, M

AU - Hezode, Christophe

AU - Hofer, H

AU - Husa, P

AU - Idilman, Ramazan

AU - Kaberg, M

AU - Kaita, Kelly

AU - Kautz, Achim

AU - Kaymakoglu, Sabahattin

AU - Krajden, Mel

AU - Krarup, H

AU - Laleman, Wim J

AU - Lavanchy, D

AU - Lazaro, P

AU - Marotta, P

AU - Mauss, Stefan

AU - Mendes-Correa, Maria Cassia Jacintho

AU - Mullhaupt, B

AU - Myers, Robert P

AU - Negro, Francesco

AU - Nemecek, V

AU - Ormeci, Necati

AU - Parkes, J

AU - Peltekian, Kevork Minas

AU - Ramji, Alnoor S

AU - Razavi, Homie A

AU - Reis, N

AU - Roberts, Stuart Keith

AU - Rosenberg, William M C

AU - Sarmento-Castro, Rui

AU - Sarrazin, Christoph M

AU - Semela, David

AU - Shiha, Gamal Elsayed

AU - Sievert, William

AU - Starkel, Peter

AU - Stauber, R E

AU - Thompson, Alexander James V

AU - Urbanek, P

AU - Van Thiel, I

AU - Van Vlierberghe, H

AU - Vandijck, Dominique M

AU - Vogel, W

AU - Waked, Imam A

AU - Wedemeyer, Heiner

AU - Weis, N

AU - Wiegand, Johannes

AU - Yosry, Ayman

AU - Zekry, Amany

AU - Van Damme, P

AU - Aleman, Soo

AU - Hindman, S J

PY - 2014

Y1 - 2014

N2 - Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3 in Austria, England and Germany to 8.5 in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.

AB - Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3 in Austria, England and Germany to 8.5 in Egypt. The largest viremic populations were in Egypt, with 6,358,000 cases in 2008 and Brazil with 2,106,000 cases in 2007. The age distribution of cases differed between countries. In most countries, prevalence rates were higher among males, reflecting higher rates of injection drug use. Diagnosis, treatment and transplant levels also differed considerably between countries. Reliable estimates characterizing HCV-infected populations are critical for addressing HCV-related morbidity and mortality. There is a need to quantify the burden of chronic HCV infection at the national level.

UR - http://www.ncbi.nlm.nih.gov/pubmed/24713004

U2 - 10.1111/jvh.12247

DO - 10.1111/jvh.12247

M3 - Article

VL - 21

SP - 5

EP - 33

JO - Journal of Viral Hepatitis

JF - Journal of Viral Hepatitis

SN - 1352-0504

IS - Supplement S1

ER -

Bruggmann P, Berg T, Ovrehus ALH, Moreno CA, Brandao-Mello CE, Roudot-Thoraval F et al. Historical epidemiology of hepatitis C virus (HCV) in selected countries. Journal of Viral Hepatitis. 2014;21(Supplement S1):5 - 33. https://doi.org/10.1111/jvh.12247