Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA

Jeymohan Joseph; Paola Cinque; Deborah Colosi; Ameet Dravid; Luminita Ene; Howard S Fox; Dana Gabuzda; Magnus Gisslen; Sarah Beth Joseph; Scott Letendre; Shibani S Mukerji; Avindra Nath; Ignacio Perez-Valero; Deborah Persaud; Richard W Price; Vasudev R Rao; Ned Sacktor; Ronald Swanstrom; Alan Winston; Valerie Wojna; Edwina J. Wright; Serena Spudich

Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA

Jeymohan Joseph, Paola Cinque, Deborah Colosi, Ameet Dravid, Luminita Ene, Howard S Fox, Dana Gabuzda, Magnus Gisslen, Sarah Beth Joseph, Scott Letendre, Shibani S Mukerji, Avindra Nath, Ignacio Perez-Valero, Deborah Persaud, Richard W Price, Vasudev R Rao, Ned Sacktor, Ronald Swanstrom, Alan Winston, Valerie WojnaEdwina J. Wright, Serena Spudich

Infectious Diseases

Research output: Contribution to journal › Conference article › Other › peer-review

Abstract

CSF HIV escape is a recently recognised phenomenon that suggests that despite suppressive treatment, HIV RNA may be detected in the CNS compartment in some individuals. In rare cases this is associated with clinical neurological disease, while in most cases, neurological consequences are not apparent. Attempts at characterising the biological substrates of CSF escape and further investigating the neurological consequences need to be made to better understand the implications of this condition for the HIV cure agenda as well as for clinical outcomes. The Global CSF HIV-1 Escape Consortium meeting, convened by the US National Institute of Mental Health, was a first step to gather investigators from diverse sites to discuss opportunities for future collaborative work on this emerging issue. To better understand CSF HIV escape and allow cross-site data reconciliation, it will be useful to reach a consensus set of definitions of the distinct forms of CSF escape, without which concerted cross-site efforts are difficult.

Original language	English
Pages (from-to)	243-250
Number of pages	8
Journal	Journal of Virus Eradication
Volume	2
Issue number	4
Publication status	Published - Oct 2016

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

Joseph, J., Cinque, P., Colosi, D., Dravid, A., Ene, L., Fox, H. S., Gabuzda, D., Gisslen, M., Joseph, S. B., Letendre, S., Mukerji, S. S., Nath, A., Perez-Valero, I., Persaud, D., Price, R. W., Rao, V. R., Sacktor, N., Swanstrom, R., Winston, A., ... Spudich, S. (2016). Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA. Journal of Virus Eradication, 2(4), 243-250.

@article{f9890adf3494475093e07095e66365f9,

title = "Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA",

abstract = "CSF HIV escape is a recently recognised phenomenon that suggests that despite suppressive treatment, HIV RNA may be detected in the CNS compartment in some individuals. In rare cases this is associated with clinical neurological disease, while in most cases, neurological consequences are not apparent. Attempts at characterising the biological substrates of CSF escape and further investigating the neurological consequences need to be made to better understand the implications of this condition for the HIV cure agenda as well as for clinical outcomes. The Global CSF HIV-1 Escape Consortium meeting, convened by the US National Institute of Mental Health, was a first step to gather investigators from diverse sites to discuss opportunities for future collaborative work on this emerging issue. To better understand CSF HIV escape and allow cross-site data reconciliation, it will be useful to reach a consensus set of definitions of the distinct forms of CSF escape, without which concerted cross-site efforts are difficult.",

author = "Jeymohan Joseph and Paola Cinque and Deborah Colosi and Ameet Dravid and Luminita Ene and Fox, {Howard S} and Dana Gabuzda and Magnus Gisslen and Joseph, {Sarah Beth} and Scott Letendre and Mukerji, {Shibani S} and Avindra Nath and Ignacio Perez-Valero and Deborah Persaud and Price, {Richard W} and Rao, {Vasudev R} and Ned Sacktor and Ronald Swanstrom and Alan Winston and Valerie Wojna and Wright, {Edwina J.} and Serena Spudich",

year = "2016",

month = oct,

language = "English",

volume = "2",

pages = "243--250",

journal = "Journal of Virus Eradication",

issn = "2055-6640",

publisher = "Mediscript Ltd.",

number = "4",

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Joseph, J, Cinque, P, Colosi, D, Dravid, A, Ene, L, Fox, HS, Gabuzda, D, Gisslen, M, Joseph, SB, Letendre, S, Mukerji, SS, Nath, A, Perez-Valero, I, Persaud, D, Price, RW, Rao, VR, Sacktor, N, Swanstrom, R, Winston, A, Wojna, V, Wright, EJ & Spudich, S 2016, 'Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA', Journal of Virus Eradication, vol. 2, no. 4, pp. 243-250.

TY - JOUR

T1 - Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA

AU - Joseph, Jeymohan

AU - Cinque, Paola

AU - Colosi, Deborah

AU - Dravid, Ameet

AU - Ene, Luminita

AU - Fox, Howard S

AU - Gabuzda, Dana

AU - Gisslen, Magnus

AU - Joseph, Sarah Beth

AU - Letendre, Scott

AU - Mukerji, Shibani S

AU - Nath, Avindra

AU - Perez-Valero, Ignacio

AU - Persaud, Deborah

AU - Price, Richard W

AU - Rao, Vasudev R

AU - Sacktor, Ned

AU - Swanstrom, Ronald

AU - Winston, Alan

AU - Wojna, Valerie

AU - Wright, Edwina J.

AU - Spudich, Serena

PY - 2016/10

Y1 - 2016/10

N2 - CSF HIV escape is a recently recognised phenomenon that suggests that despite suppressive treatment, HIV RNA may be detected in the CNS compartment in some individuals. In rare cases this is associated with clinical neurological disease, while in most cases, neurological consequences are not apparent. Attempts at characterising the biological substrates of CSF escape and further investigating the neurological consequences need to be made to better understand the implications of this condition for the HIV cure agenda as well as for clinical outcomes. The Global CSF HIV-1 Escape Consortium meeting, convened by the US National Institute of Mental Health, was a first step to gather investigators from diverse sites to discuss opportunities for future collaborative work on this emerging issue. To better understand CSF HIV escape and allow cross-site data reconciliation, it will be useful to reach a consensus set of definitions of the distinct forms of CSF escape, without which concerted cross-site efforts are difficult.

AB - CSF HIV escape is a recently recognised phenomenon that suggests that despite suppressive treatment, HIV RNA may be detected in the CNS compartment in some individuals. In rare cases this is associated with clinical neurological disease, while in most cases, neurological consequences are not apparent. Attempts at characterising the biological substrates of CSF escape and further investigating the neurological consequences need to be made to better understand the implications of this condition for the HIV cure agenda as well as for clinical outcomes. The Global CSF HIV-1 Escape Consortium meeting, convened by the US National Institute of Mental Health, was a first step to gather investigators from diverse sites to discuss opportunities for future collaborative work on this emerging issue. To better understand CSF HIV escape and allow cross-site data reconciliation, it will be useful to reach a consensus set of definitions of the distinct forms of CSF escape, without which concerted cross-site efforts are difficult.

M3 - Conference article

SN - 2055-6640

VL - 2

SP - 243

EP - 250

JO - Journal of Virus Eradication

JF - Journal of Virus Eradication

IS - 4

ER -